2021
The Impact of Intracytoplasmic Sperm Injection in Non-Male Factor Infertility—A Critical Review
Glenn TL, Kotlyar AM, Seifer DB. The Impact of Intracytoplasmic Sperm Injection in Non-Male Factor Infertility—A Critical Review. Journal Of Clinical Medicine 2021, 10: 2616. PMID: 34198564, PMCID: PMC8231975, DOI: 10.3390/jcm10122616.Peer-Reviewed Original ResearchNon-male factor infertilityUse of ICSIIntracytoplasmic sperm injectionTotal fertilization failureFactor infertilityMale factor infertilityFertilization failureSperm injectionSafety of offspringLive birth rateFertilization rateICSI useSurveillance studyInfertilityBirth rateHigh rateInjectionNumerous studiesFailurePatientsIVF
2020
Do state insurance mandates alter ICSI utilization?
Zagadailov P, Seifer DB, Shan H, Zarek SM, Hsu AL. Do state insurance mandates alter ICSI utilization? Reproductive Biology And Endocrinology 2020, 18: 33. PMID: 32334609, PMCID: PMC7183130, DOI: 10.1186/s12958-020-00589-w.Peer-Reviewed Original ResearchConceptsIntracytoplasmic sperm injectionElective single embryo transferClinical pregnancyICSI usePreimplantation genetic testingESET rateState insurance mandatesTwin rateInsurance mandatesRetrospective cohort studyLive birth rateLower clinical pregnancyMale factor infertilitySingle embryo transferBirth rateTwin birth rateT-testICSI rateLower LBRStrength of associationCohort studyFactor infertilityART cyclesResultsFrom 2000ART coverage
2018
Temporal Differences in Utilization of Intracytoplasmic Sperm Injection Among U.S. Regions
Zagadailov P, Hsu A, Stern JE, Seifer DB. Temporal Differences in Utilization of Intracytoplasmic Sperm Injection Among U.S. Regions. Obstetrics And Gynecology 2018, 132: 310-320. PMID: 29995722, DOI: 10.1097/aog.0000000000002730.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCohort StudiesFemaleFertilization in VitroHumansInfertility, FemaleInfertility, MaleLive BirthMalePregnancyPregnancy RateRetrospective StudiesSperm Injections, IntracytoplasmicTreatment OutcomeUnited StatesUnited States Dept. of Health and Human ServicesYoung AdultConceptsLive birth rateUse of ICSIICSI rateICSI utilizationBirth rateRetrospective cohort studyMale factor infertilityHuman Services (HHS) regionsIntracytoplasmic sperm injectionYears of agePreimplantation genetic testingMale factor diagnosisDepartment of HealthNondonor cyclesCohort studyFertilization cyclesFactor infertilityMale factorSperm injectionMedical indicationsMagnitude of increaseClinicGenetic testingDisease controlICSI
2017
Differences in utilization of Intracytoplasmic sperm injection (ICSI) within human services (HHS) regions and metropolitan megaregions in the U.S.
Zagadailov P, Hsu A, Seifer DB, Stern JE. Differences in utilization of Intracytoplasmic sperm injection (ICSI) within human services (HHS) regions and metropolitan megaregions in the U.S. Reproductive Biology And Endocrinology 2017, 15: 45. PMID: 28606175, PMCID: PMC5469007, DOI: 10.1186/s12958-017-0263-4.Peer-Reviewed Original ResearchConceptsLive birth rateIntracytoplasmic sperm injectionHuman Services (HHS) regionsBirth rateUse of ICSIHigher live birth rateNon-donor cyclesUS practice patternsMale factor infertilityHigh rateDepartment of HealthFactor infertilityMale factorPractice patternsInfertility rateClinic groupSperm injectionHuman service groupsDisease controlWomenClinicInfertilityLower ratesService regionArt differs
2014
Antimüllerian hormone as predictor of implantation and clinical pregnancy after assisted conception: a systematic review and meta-analysis
Tal R, Tal O, Seifer BJ, Seifer DB. Antimüllerian hormone as predictor of implantation and clinical pregnancy after assisted conception: a systematic review and meta-analysis. Fertility And Sterility 2014, 103: 119-130.e3. PMID: 25450298, DOI: 10.1016/j.fertnstert.2014.09.041.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Mullerian HormoneBiomarkersEmbryo ImplantationFemaleFertilization in VitroHumansInfertility, FemaleMiddle AgedObservational Studies as TopicOvarian ReserveOvaryOvulation InductionPregnancyPregnancy OutcomePregnancy RatePrevalenceReproducibility of ResultsRisk FactorsSensitivity and SpecificityYoung AdultConceptsPredictor of implantationClinical pregnancy rateAntimüllerian hormoneClinical pregnancyOvarian reservePregnancy rateOdds ratioIVF/intracytoplasmic sperm injectionSystematic reviewSerum AMH levelsPolycystic ovary syndromeReproductive technologiesIntracytoplasmic sperm injectionNondonor cyclesAMH levelsOvary syndromeImplantation rateDiagnostic odds ratioObservational studyMAIN OUTCOMEClinical utilitySperm injectionPregnancyAssisted conceptionFertility treatmentAssisted hatching and intracytoplasmic sperm injection are not associated with improved outcomes in assisted reproduction cycles for diminished ovarian reserve: an analysis of cycles in the United States from 2004 to 2011
Butts SF, Owen C, Mainigi M, Senapati S, Seifer DB, Dokras A. Assisted hatching and intracytoplasmic sperm injection are not associated with improved outcomes in assisted reproduction cycles for diminished ovarian reserve: an analysis of cycles in the United States from 2004 to 2011. Fertility And Sterility 2014, 102: 1041-1047.e1. PMID: 25086790, PMCID: PMC4184996, DOI: 10.1016/j.fertnstert.2014.06.043.Peer-Reviewed Original ResearchMeSH KeywordsChi-Square DistributionEmbryo Culture TechniquesEmbryo TransferFemaleHumansInfertility, FemaleLive BirthLogistic ModelsOdds RatioOvarian ReservePregnancyPregnancy RatePrimary Ovarian InsufficiencyRegistriesRetrospective StudiesRisk FactorsSperm Injections, IntracytoplasmicTime FactorsTreatment OutcomeUnited StatesConceptsDiminished ovarian reserveIntracytoplasmic sperm injectionElevated FSHLive birthsOvarian reserveART cyclesSperm injectionAssisted Reproductive Technology Clinic Outcome Reporting System databaseClinical pregnancy rateRetrospective cohort studyLive birth rateReproductive technology outcomesAssisted reproduction cyclesCombination of ICSIReporting System databaseCohort studyPrimary diagnosisImproved outcomesPregnancy rateMAIN OUTCOMELower oddsDiminished oddsFSHOnly indicationTechnology outcomes
2006
Immunocytochemical evidence for the presence and location of the neurotrophin–Trk receptor family in adult human preovulatory ovarian follicles
Seifer DB, Feng B, Shelden RM. Immunocytochemical evidence for the presence and location of the neurotrophin–Trk receptor family in adult human preovulatory ovarian follicles. American Journal Of Obstetrics And Gynecology 2006, 194: 1129-1134. PMID: 16580310, DOI: 10.1016/j.ajog.2005.12.022.Peer-Reviewed Original ResearchConceptsHuman preovulatory folliclesTrk A receptorCumulus granulosa cellsTrk CTrk BPreovulatory folliclesOvarian folliclesGranulosa cellsFertilization/intracytoplasmic sperm injectionUnfertilized oocytesHuman ovarian folliclesA receptorsAbsence of neurotrophinsIntracytoplasmic sperm injectionPreovulatory ovarian folliclesRespective receptor proteinsReceptor proteinNT-4/5NT-3Prospective studyNeurotrophin receptorSperm injectionNeurotrophinsHuman unfertilized oocytesParacrine function