1987
Actions of acetylcholine in the guinea‐pig and cat medial and lateral geniculate nuclei, in vitro.
McCormick D, Prince D. Actions of acetylcholine in the guinea‐pig and cat medial and lateral geniculate nuclei, in vitro. The Journal Of Physiology 1987, 392: 147-165. PMID: 2833597, PMCID: PMC1192298, DOI: 10.1113/jphysiol.1987.sp016774.Peer-Reviewed Original ResearchConceptsRapid excitatory responseSlow depolarizationApplication of acetylcholineLateral geniculate nucleusGeniculate nucleusMuscarinic hyperpolarizationExcitatory responsesMuscarinic receptorsReversal potentialDorsal lateral geniculate nucleusGeniculate neuronesApparent input conductanceSingle spike activityIntracellular recording techniquesAction of acetylcholineACh-induced hyperpolarizationExtrapolated reversal potentialSingle-spike firingMechanism of actionMembrane potentialBath applicationBurst firingBurst dischargesSynaptic transmissionThalamic slices
1985
Two types of muscarinic response to acetylcholine in mammalian cortical neurons.
McCormick D, Prince D. Two types of muscarinic response to acetylcholine in mammalian cortical neurons. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 6344-6348. PMID: 3862134, PMCID: PMC391050, DOI: 10.1073/pnas.82.18.6344.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidInput resistanceMuscarinic responsesPyramidal neuronsPyramidal cellsInhibitory neurotransmitter gamma-aminobutyric acidNeurotransmitter gamma-aminobutyric acidShort-latency depolarizationsShort-latency inhibitionMammalian cortical neuronsNeuronal input resistanceSlow excitatory responsesApplication of acetylcholineVoltage-dependent depolarizationCholinergic inhibitionExcitatory responsesCholinergic receptorsVoltage-dependent increaseCortical slicesGABAergic interneuronsNicotinic antagonistsCholinergic agonistsCortical neuronsSlow depolarizationNeocortical neurons