Acetylcholine causes rapid nicotinic excitation in the medial habenular nucleus of guinea pig, in vitro
McCormick D, Prince D. Acetylcholine causes rapid nicotinic excitation in the medial habenular nucleus of guinea pig, in vitro. Journal Of Neuroscience 1987, 7: 742-752. PMID: 3549993, PMCID: PMC6569057, DOI: 10.1523/jneurosci.07-03-00742.1987.Peer-Reviewed Original ResearchConceptsMedial habenular nucleusInhibitory responsesMHb neuronsNicotinic receptorsHabenular nucleusACh-induced depolarizationMuscarinic antagonist atropineNicotinic antagonist hexamethoniumIntracellular recording techniquesEffects of AChAction of AChApplication of AChNicotinic agonist nicotineApplication of glutamateAverage reversal potentialNicotinic excitationNicotinic typePostexcitatory inhibitionAntagonist atropineAntagonist hexamethoniumMembrane conductanceACh actionACh responseCentral effectsCholinergic transmission