2012
Warm Body Temperature Facilitates Energy Efficient Cortical Action Potentials
Yu Y, Hill A, McCormick D. Warm Body Temperature Facilitates Energy Efficient Cortical Action Potentials. PLOS Computational Biology 2012, 8: e1002456. PMID: 22511855, PMCID: PMC3325181, DOI: 10.1371/journal.pcbi.1002456.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsBody TemperatureBrainComputer SimulationEnergy TransferHumansModels, NeurologicalNeuronsConceptsAction potentialsFiring rateBody temperatureFunctional brain imaging signalsAction potential durationSingle action potentialCortical action potentialsAction potential generationNormal body temperatureSpike firing rateAverage firing rateSpike afterhyperpolarizationEfficient neural codesPotential durationBrain imaging signalsMarked reductionChannel inactivationPotential generationNeural signal transmissionBrain architectureWarmer body temperaturesImaging signalsNeural codeDurationAfterhyperpolarization
2010
Endogenous Electric Fields May Guide Neocortical Network Activity
Fröhlich F, McCormick DA. Endogenous Electric Fields May Guide Neocortical Network Activity. Neuron 2010, 67: 129-143. PMID: 20624597, PMCID: PMC3139922, DOI: 10.1016/j.neuron.2010.06.005.Peer-Reviewed Original Research
2006
Neocortical Network Activity In Vivo Is Generated through a Dynamic Balance of Excitation and Inhibition
Haider B, Duque A, Hasenstaub A, McCormick D. Neocortical Network Activity In Vivo Is Generated through a Dynamic Balance of Excitation and Inhibition. Journal Of Neuroscience 2006, 26: 4535-4545. PMID: 16641233, PMCID: PMC6674060, DOI: 10.1523/jneurosci.5297-05.2006.Peer-Reviewed Original ResearchConceptsCerebral cortexNeocortical network activityReversal potentialUp statesPersistent network activityNetwork activityDepolarized reversal potentialSpontaneous network activityField potential recordingsLocal cortical circuitsLocal field potential recordingsNeuronal responsivenessCortical functionRecurrent excitatoryCortical circuitsSynaptic currentsPotential recordingsRecurrent excitationExcitatory conductancePrefrontal cortexInhibitory connectionsCortexStable network statesSlow oscillationsInhibition