1994
Enhanced activation of NMDA receptor responses at the immature retinogeniculate synapse
Ramoa A, McCormick D. Enhanced activation of NMDA receptor responses at the immature retinogeniculate synapse. Journal Of Neuroscience 1994, 14: 2098-2105. PMID: 7908957, PMCID: PMC6577156, DOI: 10.1523/jneurosci.14-04-02098.1994.Peer-Reviewed Original ResearchMeSH Keywords2-Amino-5-phosphonovalerate6-Cyano-7-nitroquinoxaline-2,3-dioneAfferent PathwaysAgingAnimalsBicucullineElectric StimulationEvoked PotentialsFerretsGeniculate BodiesIn Vitro TechniquesKineticsNeuronsQuinoxalinesReceptors, N-Methyl-D-AspartateRetinaSynapsesSynaptic TransmissionTime FactorsVisual PathwaysConceptsNMDA receptorsBicuculline methiodideNMDA-EPSCsPostnatal monthPostnatal weekGABAA receptor-mediated IPSPsAMPA/kainate receptorsOptic tract stimulationReceptor-mediated IPSPsExcitatory postsynaptic currentsNMDA receptor responsesFirst postnatal monthSecond postnatal weekVoltage-clamp recordingsDorsal LGNEPSC durationRetinogeniculate transmissionD-APVSlow EPSPTract stimulationExcitatory transmissionGABAergic inhibitionNeonatal ageRetinogeniculate synapsePostsynaptic currents
1993
Neurotransmitter Control of Neocortical Neuronal Activity and Excitability
McCormick D, Wang Z, Huguenard J. Neurotransmitter Control of Neocortical Neuronal Activity and Excitability. Cerebral Cortex 1993, 3: 387-398. PMID: 7903176, DOI: 10.1093/cercor/3.5.387.Peer-Reviewed Original ResearchConceptsActivation of muscarinicMetabotropic receptorsPyramidal cellsLayers II/IIISingle spike activityGlutamate metabotropic receptorsDuration of EPSPsAction potential generationSpike frequency adaptationCurrent IAHPGABAergic neuronsCortical neuronsGABAA receptorsNMDA receptorsH2-histaminergicNeurotransmitter systemsNeurons resultsSerotoninergic receptorsCortical circuitsNeuronal activityNeurotransmitter controlNeuronal circuitsNeocortical neuronal activityAlpha 1Functional activation