2014
The Tumor Radiobiology of SRS and SBRT: Are More Than the 5 Rs Involved?
Brown JM, Carlson DJ, Brenner DJ. The Tumor Radiobiology of SRS and SBRT: Are More Than the 5 Rs Involved? International Journal Of Radiation Oncology • Biology • Physics 2014, 88: 254-262. PMID: 24411596, PMCID: PMC3893711, DOI: 10.1016/j.ijrobp.2013.07.022.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnimalsCell CycleCell HypoxiaCell ProliferationCell SurvivalDNA DamageDNA RepairDose Fractionation, RadiationEndothelial CellsHumansLinear ModelsMelanomaMiceModels, BiologicalNeoplasmsOxygen ConsumptionRadiation ToleranceRadiobiologyRadiosurgeryRelative Biological Effectiveness
2013
A molecular dynamics simulation of DNA damage induction by ionizing radiation
Abolfath RM, Carlson DJ, Chen ZJ, Nath R. A molecular dynamics simulation of DNA damage induction by ionizing radiation. Physics In Medicine And Biology 2013, 58: 7143-7157. PMID: 24052159, DOI: 10.1088/0031-9155/58/20/7143.Peer-Reviewed Original ResearchConceptsMolecular dynamics simulationsChemical reactionsDynamics simulationsChemical bond breaksWater moleculesMolecular dynamics softwareHydrogen abstractionHydroxyl free radicalsBond breaksChemical eventsCollection of ionsSingle protonRadicalsLow-energy electronsDNA moleculesProtonsBackbone damageFree radicalsMulti-scale simulationsIonsMoleculesReactionElectronsBroken bondsEnergy electrons
2011
Effects of Radiation Quality and Oxygen on Clustered DNA Lesions and Cell Death
Stewart RD, Yu VK, Georgakilas AG, Koumenis C, Park JH, Carlson DJ. Effects of Radiation Quality and Oxygen on Clustered DNA Lesions and Cell Death. Radiation Research 2011, 176: 587-602. PMID: 21823972, DOI: 10.1667/rr2663.1.Peer-Reviewed Original Research