1996
Increased macrophage uptake of irreversibly glycated albumin modified-low density lipoproteins of normal and diabetic subjects is mediated by non-saturable mechanisms
Dobrian A, Lazar V, Tirziu D, Simionescu M. Increased macrophage uptake of irreversibly glycated albumin modified-low density lipoproteins of normal and diabetic subjects is mediated by non-saturable mechanisms. Biochimica Et Biophysica Acta 1996, 1317: 5-14. PMID: 8876621, DOI: 10.1016/0925-4439(96)00017-8.Peer-Reviewed Original ResearchConceptsAGE-AlbAdvanced glycosylation end productsDiabetic subjectsDensity lipoproteinAGE-albuminModified-low density lipoproteinsMacrophage uptakeOxidative-antioxidative balanceIndependent risk factorNon-saturable pathwayLow-density lipoproteinNon-saturable mechanismReceptor-mediated uptakeGlycosylation end productsLevel of glycationDiabetes mellitusDiabetic stateRisk factorsAtherosclerotic plaquesLipid peroxidesAcetylated LDLPeritoneal macrophagesReceptor pathwayLipoproteinDLDL
1995
Intimal thickenings of human aorta contain modified reassembled lipoproteins
Tîrziu D, Dobrian A, Tasca C, Simionescu M, Simionescu N. Intimal thickenings of human aorta contain modified reassembled lipoproteins. Atherosclerosis 1995, 112: 101-114. PMID: 7772061, DOI: 10.1016/0021-9150(94)05405-8.Peer-Reviewed Original Research