Autocrine actions of endothelin-1 as a growth factor in human ovarian carcinoma cells.
Bagnato A, Tecce R, Moretti C, Di Castro V, Spergel D, Catt K. Autocrine actions of endothelin-1 as a growth factor in human ovarian carcinoma cells. Clinical Cancer Research 1995, 1: 1059-66. PMID: 9816080.Peer-Reviewed Original ResearchConceptsOvarian carcinoma cellsHuman ovarian carcinoma cellsET-1ETA receptorsEndothelin-1Carcinoma cellsTumor cellsCell linesGrowth factorCertain ovarian tumorsET-1 participatesReceptor-mediated actionsOVCA 433 cellsOvarian tumor cell linesCalcium signalingDose-dependent increaseRadioligand binding studiesOvarian tumor cellsAutocrine growth factorOvarian cancer cellsSites/cellBasal growth rateAuthentic ET-1BQ-123ET receptors