2001
Using reporter genes to label selected neuronal populations in transgenic mice for gene promoter, anatomical, and physiological studies
Spergel D, Krüth U, Shimshek D, Sprengel R, Seeburg P. Using reporter genes to label selected neuronal populations in transgenic mice for gene promoter, anatomical, and physiological studies. Progress In Neurobiology 2001, 63: 673-686. PMID: 11165000, DOI: 10.1016/s0301-0082(00)00038-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGreen fluorescent proteinReporter geneGene promoterSubcellular localization signalsCell type-specific expressionPromoter-driven reporter geneCorresponding reporter genesType-specific expressionLocalization signalReporter proteinNeuronal populationsPromoter elementsTransgenic miceFluorescent proteinTransgenic expressionGenesCell typesGonadotropin-releasing hormone (GnRH) neuronsGnRH neuronal networkPhysiological studiesPromoterProteinHormone neuronsBla genesExpression
1994
Gonadotropin-releasing hormone neurons Intrinsic pulsatility and receptor-mediated regulation
Stojilkovic S, Krsmanovic L, Spergel D, Catt K. Gonadotropin-releasing hormone neurons Intrinsic pulsatility and receptor-mediated regulation. Trends In Endocrinology And Metabolism 1994, 5: 201-209. PMID: 18407209, DOI: 10.1016/1043-2760(94)90078-7.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsGnRH neuronsGonadotropin-releasing hormone releaseImmortalized GnRH neuronsIndividual GnRH neuronsGnRH pulse generatorPulse generator activityReceptor-mediated regulationGnRH releaseSynaptic contactsHormone releasePulsatile patternGenerator activityNeuronsEpisodic patternSecretory mechanismCell typesPulse generatorEndothelinGnRHGonadotropinHypothalamusAgonistsCatecholaminesGABAPulsatility