2024
Cefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion
Dhodapkar M, Jeong S, Halperin S, Rubio D, Li M, Grauer J. Cefazolin Alone Versus Cefazolin with Tobramycin or Gentamicin as Intraoperative Antibiotic Prophylaxis for Single-Level Posterior Lumbar Fusion. JAAOS Global Research And Reviews 2024, 8: e24.00082. PMCID: PMC11068128, DOI: 10.5435/jaaosglobal-d-24-00082.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSurgical site infectionElixhauser Comorbidity IndexLumbar fusionAntibiotic prophylaxisAdverse outcomesAntibiotic prophylaxis regimenAntibiotic prophylaxis regimensIntraoperative antibiotic prophylaxisRevision ratePerioperative antibiotic prophylaxisPostoperative adverse outcomesPosterior lumbar fusion patientsMultivariate logistic regressionProphylaxis regimensProphylaxis regimenPatient ageSite infectionUnivariate analysisCefazolinComorbidity indexMultivariate analysisAntibiotic subgroupsTraumatic diagnoses
2022
Postoperative spine surgical site infections: high rate of failure of one-stage irrigation and debridement
Dhodapkar M, Galivanche A, Halperin S, Elaydi A, Rubio D, Grauer J. Postoperative spine surgical site infections: high rate of failure of one-stage irrigation and debridement. The Spine Journal 2022, 23: 484-491. PMID: 36549456, DOI: 10.1016/j.spinee.2022.12.005.Peer-Reviewed Original ResearchConceptsSurgical site infectionElective spine surgerySpine surgeryInitial managementRate of SSIInfection characteristicsSpine surgical site infectionPostoperative surgical site infectionRetrospective case-control studyPresence of bacteremiaRisk stratification toolCase-control studySingle academic institutionTimes greater oddsDevastating complicationSite infectionMultivariable analysisStratification toolSurgical managementSurgical variablesIndex procedureSurgical interventionRisk factorsInclusion criteriaLarge cohort