2012
An fMRI Study of the Interactions Between the Attention and the Gustatory Networks
Veldhuizen MG, Gitelman DR, Small DM. An fMRI Study of the Interactions Between the Attention and the Gustatory Networks. Chemosensory Perception 2012, 5: 117-127. PMID: 25419265, PMCID: PMC4239214, DOI: 10.1007/s12078-012-9122-z.Peer-Reviewed Original ResearchAnterior cingulate cortexFrontal eye fieldCingulate cortexPosterior parietal cortexGustatory cortexEye fieldParietal operculumParietal cortexFrontal operculumAnterior insulaRight anterior insulaPsychophysiological interaction analysisCortexDynamic causal modelingCortex actsIndirect modulationFMRI studyBrain responsesInsulaGoal-directed behaviorIncoming sensory signalsConnectivity analysisSensory signalsCurrent studyAttention task
2011
Youth at Risk for Obesity Show Greater Activation of Striatal and Somatosensory Regions to Food
Stice E, Yokum S, Burger KS, Epstein LH, Small DM. Youth at Risk for Obesity Show Greater Activation of Striatal and Somatosensory Regions to Food. Journal Of Neuroscience 2011, 31: 4360-4366. PMID: 21430137, PMCID: PMC3260083, DOI: 10.1523/jneurosci.6604-10.2011.Peer-Reviewed Original ResearchConceptsNormal weight humansObese humansStriatal responsesFood intakeOrbitofrontal cortexDopamine signalingWeight gainInitial vulnerability factorsGenetic riskStriatal D2 receptorsMonetary rewardsNormal-weight adolescentsPalatable food intakeD2 receptor densityD2 receptorsHigh-risk youthParietal operculumReceptor densitySomatosensory regionsPalatable foodFoods contributesFrontal operculumReward circuitryReduced dopamineObesity