2024
Low-input lipidomics reveals lipid metabolism remodelling during early mammalian embryo development
Zhang L, Zhao J, Lam S, Chen L, Gao Y, Wang W, Xu Y, Tan T, Yu H, Zhang M, Liao X, Wu M, Zhang T, Huang J, Li B, Zhou Q, Shen N, Lee H, Ye C, Li D, Shui G, Zhang J. Low-input lipidomics reveals lipid metabolism remodelling during early mammalian embryo development. Nature Cell Biology 2024, 26: 278-293. PMID: 38302721, DOI: 10.1038/s41556-023-01341-3.Peer-Reviewed Original ResearchConceptsMammalian preimplantation embryo developmentEmbryo developmentIn vitro blastocyst developmentPreimplantation embryo developmentEight-cell embryosMammalian early embryonic developmentMammalian embryo developmentDegree of phospholipid unsaturationEarly embryo developmentApical-basal polarityBlastocyst developmentBlastocyst stageLipid metabolism remodelingHuman early embryo developmentBlastocyst implantationRegulation of embryogenesisEarly embryonic developmentBlastocystLipid landscapeApical proteinsLipid desaturasesMetabolic remodelingCell signalingPlasma membraneLipid signatures
2023
Live birth following an innovative artificial oocyte activation protocol using double calcium stimulators
Gao Y, Yang D, Fang Y, Wang X, Li D. Live birth following an innovative artificial oocyte activation protocol using double calcium stimulators. Chinese Medical Journal 2023, 136: 2101-2103. PMID: 36914951, PMCID: PMC10476707, DOI: 10.1097/cm9.0000000000002407.Peer-Reviewed Original Research