2021
Risk of Intestinal Necrosis With Sodium Polystyrene Sulfonate: A Systematic Review and Meta‐analysis
Holleck JL, Roberts AE, Marhoffer EA, Grimshaw AA, Gunderson CG. Risk of Intestinal Necrosis With Sodium Polystyrene Sulfonate: A Systematic Review and Meta‐analysis. Journal Of Hospital Medicine 2021, 16: 489-494. PMID: 34328838, DOI: 10.12788/jhm.3655.Peer-Reviewed Original ResearchConceptsSevere gastrointestinal side effectsGastrointestinal side effectsIntestinal necrosisHazard ratioSide effectsComposite outcomeOdds ratioSodium polystyrene sulfonateSystematic reviewSevere gastrointestinal adverse eventsGastrointestinal adverse eventsPooled hazard ratioRisk of biasPooled odds ratioCase-control studyPrior systematic reviewsSystematic literature searchAdverse eventsAlternative medicationsCochrane LibraryDatabase inceptionClinical trialsNecrosis rateInclusion criteriaPotential confounding
2020
Prevalence of harmful diagnostic errors in hospitalised adults: a systematic review and meta-analysis
Gunderson CG, Bilan VP, Holleck JL, Nickerson P, Cherry BM, Chui P, Bastian LA, Grimshaw AA, Rodwin BA. Prevalence of harmful diagnostic errors in hospitalised adults: a systematic review and meta-analysis. BMJ Quality & Safety 2020, 29: 1008-1018. PMID: 32269070, DOI: 10.1136/bmjqs-2019-010822.Peer-Reviewed Original ResearchConceptsAdverse eventsDiagnostic errorsPhysician reviewSystematic reviewInpatient adverse eventsRisk of biasPatient safety hazardsSystem-related factorsSystematic literature searchWeb of SciencePulmonary embolismAdult patientsCase seriesCommon diagnosisPooled rateAdult admissionsCochrane LibraryDatabase inceptionDiagnostic error rateStudy characteristicsLiterature searchPatientsCommon diseaseDiagnosisCommon being
2019
Symptom-Triggered Therapy for Alcohol Withdrawal Syndrome: a Systematic Review and Meta-analysis of Randomized Controlled Trials
Holleck JL, Merchant N, Gunderson CG. Symptom-Triggered Therapy for Alcohol Withdrawal Syndrome: a Systematic Review and Meta-analysis of Randomized Controlled Trials. Journal Of General Internal Medicine 2019, 34: 1018-1024. PMID: 30937668, PMCID: PMC6544709, DOI: 10.1007/s11606-019-04899-7.Peer-Reviewed Original ResearchConceptsSymptom-triggered therapyDuration of therapyAlcohol withdrawal syndromeBenzodiazepine doseWithdrawal syndromeTrial of patientsLow-risk patientsGeneral hospital settingRandomized Controlled TrialsRisk of biasTerms of mortalitySystematic literature searchStrength of evidenceBenzodiazepine dosageDose therapyMedication classesCochrane RegistryCochrane riskDose regimensAlcohol withdrawalBias toolControlled TrialsDose scheduleResultsSix studiesI2 statistic