2025
16 Metabolic Syndrome and Obesity
Alonso W, Canapari C. 16 Metabolic Syndrome and Obesity. 2025, 175-184. DOI: 10.1016/b978-0-323-75566-5.00016-2.Peer-Reviewed Original ResearchMetabolic syndromeComponents of metabolic syndromeInvolvement of adipocytokinesSleep-disordered breathingIncreased sympathetic activityElevated blood pressureCardiovascular risk factorsRates of obesityIntermittent hypoxemiaTruncal obesityDysregulation of glucose metabolismSleep fragmentationSympathetic activityBlood pressureSleep curtailmentRisk factorsSyndromeObesityShort sleepGlucose metabolismCircadian factorsSleepHypoxemiaDyslipidemiaAdipocytokines
2024
Screening and Evaluation of Sleep Disturbances and Sleep Disorders in Children and Adolescents
Baddam S, Canapari C, Van de Grift J, McGirr C, Nasser A, Crowley M. Screening and Evaluation of Sleep Disturbances and Sleep Disorders in Children and Adolescents. Psychiatric Clinics Of North America 2024, 47: 65-86. PMID: 38302214, DOI: 10.1016/j.psc.2023.06.005.Peer-Reviewed Original ResearchConceptsSleep disturbancePediatric mental health clinicsPediatric mental healthPrimary care clinicsMental health clinicsMental health disordersSleep disordersEvaluation of sleep disturbancesCare clinicsHealth clinicsMental healthTreatment of sleep disturbancesHealth disordersConsumer wearablesPediatric clinicScreening toolUnder-recognizedEvaluation toolSleep assessmentChildren/adolescentsBidirectional relationshipClinicDisordersSleepSleep telemedicineWhen lungs and weights tell different stories
Godse S, Brumer E, Kizilirmak T, Canapari C, Silva C, Morotti R, Jiang Y, Jeffries L, Chen L, Panacherry S. When lungs and weights tell different stories. Pediatric Pulmonology 2024, 59: 1047-1059. PMID: 38353400, DOI: 10.1002/ppul.26832.Peer-Reviewed Original Research
2023
Early emergence of racial and ethnic differences in sleep health among toddlers living in low-income families
Ordway M, Sadler L, Jeon S, Pierre J, Canapari C, Redeker N. Early emergence of racial and ethnic differences in sleep health among toddlers living in low-income families. Sleep Health 2023, 9: 389-397. PMID: 37453903, PMCID: PMC10517059, DOI: 10.1016/j.sleh.2023.02.006.Peer-Reviewed Original ResearchConceptsAverage sleep durationSleep healthGroup differencesEthnic differencesBrief Infant Sleep QuestionnaireAge-based recommendationsSleep health disparitiesInfant Sleep QuestionnaireLow-income familiesMonths of ageChildren's sleep healthSleep QuestionnaireSleep durationLarge effect sizesSleep diaryBedtime variabilityActigraph dataHealth disparitiesEarlier bedtimesSociodemographic variablesSocioeconomic differencesMarital statusBedtimeEarly childhoodYoung childrenMoving toward standardization: physician reporting of sleep studies.
Lastra A, Ingram D, Park J, James E, Matthews C, Canapari C, Mansukhani M, Stahl S. Moving toward standardization: physician reporting of sleep studies. Journal Of Clinical Sleep Medicine 2023, 19: 595-603. PMID: 36546360, PMCID: PMC9978423, DOI: 10.5664/jcsm.10442.Peer-Reviewed Original ResearchConceptsSleep studiesPhysician reportingDurable medical equipment companiesEvidence-based clinical recommendationsSleep medicine specialistsSleep centerClinical recommendationsMedicine specialistsPatient careMedical equipment companiesPatientsCareCaregiversStructured reportingWindow of opportunityReportReportingWide variationClear reportStudyCliniciansSleepPhysiciansRecipients
2022
0847 Sleep Disordered Breathing in a case series of 4 children with Trisomy 18
Kochhar R, Brumer E, Canapari C. 0847 Sleep Disordered Breathing in a case series of 4 children with Trisomy 18. Sleep 2022, 45: a364-a365. DOI: 10.1093/sleep/zsac079.841.Peer-Reviewed Original ResearchPositive airway pressure therapyObstructive sleep apneaSevere obstructive sleep apneaCase seriesTrisomy 18Trisomy 21Treatment of OSAModerate obstructive sleep apneaManagement of SDBPrevalence of SDBResolution of hypoxemiaAirway pressure therapyReduced sleep efficiencySmall case seriesNon-syndromic childrenSleep Disordered BreathingTrisomy 18 patientsPAP therapyAdenoid hypertrophyEndoscopic assessmentFourth patientSeizure disorderSleep apneaSupplemental oxygenAggressive intervention
2019
0792 Parent and Provider Perceptions About Sleep in Children Living with Economic Adversity
Sadler L, Ordway M, Fenick A, O'Connell M, Banasiak N, Crowley A, Canapari C, Redeker N. 0792 Parent and Provider Perceptions About Sleep in Children Living with Economic Adversity. Sleep 2019, 42: a318-a318. DOI: 10.1093/sleep/zsz067.790.Peer-Reviewed Original ResearchSleep promotion programsSleep interventionsEconomic adversityBehavioral sleep interventionsGroups of participantsParents of childrenSleep-related outcomesParental work schedulesSocial ecological modelM ageFamily stressHours of sleepParents' perceptionsYoung familiesPediatric healthcare providersSemi-structured interviewsEthnic minority backgroundsSleep informationSleep disparitiesAdversityWork schedulesPerceptionChildcare providersPromotion programsSleep0246 Rest-activity Circadian Rhythm And Hair Cortisol Among Toddlers Living In Socioeconomically Disadvantaged Communities.
Ordway M, Jeon S, Sadler L, Canapari C, Redeker N. 0246 Rest-activity Circadian Rhythm And Hair Cortisol Among Toddlers Living In Socioeconomically Disadvantaged Communities. Sleep 2019, 42: a101-a101. DOI: 10.1093/sleep/zsz067.245.Peer-Reviewed Original ResearchRest-activity patternsHair cortisol levelsHair cortisolCortisol levelsChronic stressRest-activity circadian rhythmNon-parametric circadian rhythm analysisLower hair cortisolYoung childrenEarly childhood adversitySleep-wake rhythmHealthy toddlersProlonged stress responseChildhood adversityCertain cancersCircadian rhythm analysisSignificant sex differencesCortisolOverall exposureCircadian patternPearson correlation coefficientDaily activitiesLongitudinal analysisSex differencesToddlers
2018
0830 Sleep and Toxic Stress Among Toddlers: Associations Between Sleep and Hair Cortisol
Ordway M, Jeon S, Sadler L, Canapari C, Redeker N. 0830 Sleep and Toxic Stress Among Toddlers: Associations Between Sleep and Hair Cortisol. Sleep 2018, 41: a308-a308. DOI: 10.1093/sleep/zsy061.829.Peer-Reviewed Original ResearchNighttime sleep durationSleep characteristicsSleep efficiencySleep durationChronic stressHealth outcomesCommunity primary care clinicsHair cortisolStress response systemSocioeconomic adversityPrimary care clinicsSleep efficiency scoresShort sleep durationCross-sectional studyNocturnal sleep efficiencyModerate inverse associationPoor sleep efficiencyPoor health outcomesPoor sleep healthChildren’s stress response systemYoung childrenObjective sleep characteristicsNegative health outcomesHair cortisol levelsToxic stress
2017
0998 PARENTING INTERACTIVE BEDTIME BEHAVIORS AND SLEEP AMONG TODDLERS LIVING IN SOCIOECONOMICALLY DISADVANTAGED HOMES
Ordway, Jeon S, Canapari C, Sadler L, Redeker N. 0998 PARENTING INTERACTIVE BEDTIME BEHAVIORS AND SLEEP AMONG TODDLERS LIVING IN SOCIOECONOMICALLY DISADVANTAGED HOMES. Sleep 2017, 40: a371-a371. DOI: 10.1093/sleepj/zsx050.997.Peer-Reviewed Original ResearchSleep durationSleep characteristicsIntra-individual variabilityLess sleep durationCross-sectional studyCharacteristics of sleepPhysical comfortingSignificant moderate associationFuture intervention developmentDisadvantaged homesHigher socioeconomic statusNight wakeningsHealthy toddlersMore individual variabilitySleep fragmentationAmount of wakeCommunity clinicsSleep patternsModifiable influencesSleep onsetSleepOlder childrenBedtime behaviorsIntervention developmentSocioeconomic status
2016
Nonsurgical Management of Pediatric Obstructive Sleep Apnea
Canapari C, Cook A. Nonsurgical Management of Pediatric Obstructive Sleep Apnea. 2016, 867-867. DOI: 10.5005/jp/books/12712_70.BooksCentral Apnea in Children: Diagnosis and Management
Canapari C, Yonker L. Central Apnea in Children: Diagnosis and Management. 2016, 871-871. DOI: 10.5005/jp/books/12712_71.Books
2014
Coenzyme Q10 and immunity: A case report and new implications for treatment of recurrent infections in metabolic diseases
Farough S, Karaa A, Walker M, Slate N, Dasu T, Verbsky J, Fusunyan R, Canapari C, Kinane T, Van Cleave J, Sweetser D, Sims K, Walter J. Coenzyme Q10 and immunity: A case report and new implications for treatment of recurrent infections in metabolic diseases. Clinical Immunology 2014, 155: 209-212. PMID: 25264263, DOI: 10.1016/j.clim.2014.09.010.Peer-Reviewed Original ResearchConceptsRecurrent infectionsCoQ10 deficiencyImmunoglobulin replacement therapyFour-year-old girlCoenzyme Q10 deficiencyImmune dysfunctionImmune dysregulationReplacement therapyCase reportIsolated myopathyImmune functionMetabolic diseasesOld girlCoenzyme Q10Developmental delayInfectionDiseaseDeficiencyDysfunctionHypotoniaTherapyMyopathyImmunity
2011
A pilot study to identify pre- and peri-operative risk factors for airway complications following adenotonsillectomy for treatment of severe pediatric OSA
Hill CA, Litvak A, Canapari C, Cummings B, Collins C, Keamy DG, Ferris TG, Hartnick CJ. A pilot study to identify pre- and peri-operative risk factors for airway complications following adenotonsillectomy for treatment of severe pediatric OSA. International Journal Of Pediatric Otorhinolaryngology 2011, 75: 1385-1390. PMID: 21871668, DOI: 10.1016/j.ijporl.2011.07.034.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdenoidectomyAge FactorsChildChild, PreschoolCohort StudiesFemaleFollow-Up StudiesHumansMalePatient SelectionPilot ProjectsPostoperative CarePostoperative ComplicationsPredictive Value of TestsPreoperative CareRecurrenceRegression AnalysisRetrospective StudiesRisk AssessmentSeverity of Illness IndexSleep Apnea, ObstructiveTime FactorsTonsillectomyTreatment OutcomeConceptsPeri-operative risk factorsApnea-hypopnea indexPost-operative complicationsRisk factorsAirway complicationsSevere OSAComplication rateProspective studyPilot studyFuture prospective validation studiesTertiary care academic institutionPost-operative morbidityProspective validation studyBest-practice algorithmsPediatric OSAMinor complicationsRetrospective reviewPotential significant cost savingsICU settingPediatric floorOxygen saturationComplicationsPractice algorithmAdenotonsillectomyRoom airRelationship between sleep apnea, fat distribution, and insulin resistance in obese children.
Canapari CA, Hoppin AG, Kinane TB, Thomas BJ, Torriani M, Katz ES. Relationship between sleep apnea, fat distribution, and insulin resistance in obese children. Journal Of Clinical Sleep Medicine 2011, 7: 268-73. PMID: 21677896, PMCID: PMC3113965, DOI: 10.5664/jcsm.1068.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaHomeostasis model assessmentBody mass indexLog homeostasis model assessmentBMI z-scoreObese childrenInsulin resistanceFat distributionSleep apneaMean body mass indexSubcutaneous adipose tissue areaZ-scoreVisceral fat areaVisceral fat distributionSubset of patientsAdipose tissue areaPediatric obesity clinicSubset of subjectsMagnetic resonance imagingOSA pathogenesisObesity clinicOSA severityObese subjectsMass indexFat areaAspergilloma In A Patient With An Occult Congenital Cystic Adenomatoid Malformation
Yonker L, Mark E, Canapari C. Aspergilloma In A Patient With An Occult Congenital Cystic Adenomatoid Malformation. 2011, a1872-a1872. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a1872.Peer-Reviewed Original Research