2019
Transgenic mouse model for conditional expression of influenza hemagglutinin-tagged human SLC20A1/PIT1
Chande S, Ho B, Fetene J, Bergwitz C. Transgenic mouse model for conditional expression of influenza hemagglutinin-tagged human SLC20A1/PIT1. PLOS ONE 2019, 14: e0223052. PMID: 31613887, PMCID: PMC6793878, DOI: 10.1371/journal.pone.0223052.Peer-Reviewed Original ResearchMeSH KeywordsActinsAnimalsBeta-GlobinsBiological TransportBone DensityCalcitriolChickensCytomegalovirusFemaleFibroblast Growth Factor-23Fibroblast Growth FactorsFounder EffectHemagglutinin Glycoproteins, Influenza VirusHumansMaleMiceMice, TransgenicOsteoblastsParathyroid HormonePhosphatesPrimary Cell CulturePromoter Regions, GeneticRabbitsRecombinant Fusion ProteinsSkullTranscription Factor Pit-1TransgenesConceptsPrimary calvaria osteoblastsLoxP-stop-loxPLoxP-STOP-loxP cassetteMouse modelDihydroxy vitamin D levelsHemagglutinin (HABone mineral densityVitamin D levelsInfluenza hemagglutinin (HAConditional mouse modelActivation of transgene expressionElevated plasma PiTransgenic mouse modelPlasma iPTHUrine PiBeta-globin geneSerum calciumWT littermatesMineral densityDays of ageProtein excretionD levelsSemi-quantitative RT-PCRStandard chowTransgenic mice
2002
Cyclic-adenosine 3′,5′-monophosphate-stimulated c-fos gene transcription involves distinct calcium pathways in single β-cells
Schöfl C, Waring M, Bergwitz C, Arseniev L, von zur Mühlen A, Brabant G. Cyclic-adenosine 3′,5′-monophosphate-stimulated c-fos gene transcription involves distinct calcium pathways in single β-cells. Molecular And Cellular Endocrinology 2002, 186: 121-131. PMID: 11850128, DOI: 10.1016/s0303-7207(01)00609-8.Peer-Reviewed Original ResearchConceptsSerum response elementCa(2+)-influxC-fos gene transcriptionC-fos promoterCAMP response elementC-fosBeta-cellsModes of Ca(2+) entryGene transcriptionCa(2+) entryCa(2+C-fos mRNA expressionCa(2+) signalingForskolin-induced riseCa(2+)-free mediumForskolin-induced increaseCytosolic free calciumActivation of c-fos transcriptionCa(2+)-dependent pathwaysSingle B cellsCa(2+)-mediated mechanismsBeta-cell activityC-fos promoter activityC-fos transcriptionEffect of cAMP