Keratin 1 as a cell-surface receptor in cancer
Ogunnigbagbe O, Bunick CG, Kaur K. Keratin 1 as a cell-surface receptor in cancer. Biochimica Et Biophysica Acta (BBA) - Reviews On Cancer 2021, 1877: 188664. PMID: 34890750, PMCID: PMC8818032, DOI: 10.1016/j.bbcan.2021.188664.Peer-Reviewed Original ResearchConceptsImportant cellular functionsGlycine-rich loopType II keratinsCell surface receptorsReceptor-mediated endocytosisKeratin 1Cell surface expressionCellular functionsC-terminusCentral domainEpithelial cell markersCancer progressionIntermediate filamentsFibrous proteinsCancer cellsK1 expressionOxidative stressCancerous cellsCell markersImmune evasionCellsExpressionKeratinCsk1Endocytosis