2024
Pitfalls of PRAME Immunohistochemistry in a Large Series of Melanocytic and Nonmelanocytic Lesions With Literature Review
Turner N, Ko C, McNiff J, Galan A. Pitfalls of PRAME Immunohistochemistry in a Large Series of Melanocytic and Nonmelanocytic Lesions With Literature Review. American Journal Of Dermatopathology 2024, 46: 21-30. PMID: 37982498, DOI: 10.1097/dad.0000000000002584.Peer-Reviewed Original ResearchConceptsConventional malignant melanomaMalignant melanomaPRAME immunohistochemistryBorderline lesionsNonmelanocytic lesionsDysplastic neviAmerican Joint CommitteePathological tumor stageMalignant melanocytic proliferationsBanal melanocytic nevusUlceration statusInstitution experienceBreslow depthMean ageTumor stageClinicopathologic correlationConsecutive casesMale genderAtypical fibroxanthomaSevere atypiaJoint CommitteeLarge seriesAmbiguous melanocytic lesionsMelanocytic proliferationMalignant counterparts
2020
Discordant anti‐SARS‐CoV‐2 spike protein and RNA staining in cutaneous perniotic lesions suggests endothelial deposition of cleaved spike protein
Ko CJ, Harigopal M, Gehlhausen JR, Bosenberg M, McNiff JM, Damsky W. Discordant anti‐SARS‐CoV‐2 spike protein and RNA staining in cutaneous perniotic lesions suggests endothelial deposition of cleaved spike protein. Journal Of Cutaneous Pathology 2020, 48: 47-52. PMID: 32895985, DOI: 10.1111/cup.13866.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 spike proteinCOVID toesEccrine epitheliumEndothelial cellsSkin biopsiesSpike proteinReverse transcriptase polymerase chain reaction testingSARS-CoV-2 antibodiesPolymerase chain reaction testingSARS-CoV-2 RNAPotential pathogenetic mechanismsPositive immunohistochemical labelingSARS-CoV-2Endothelial depositionPathogenetic mechanismsImmunohistochemical stainingReaction testingImmunohistochemical labelingEccrine glandsRNA ISHImmunohistochemistrySpike RNAGold standardTissue sectionsBiopsyPerniosis during the COVID‐19 pandemic: Negative anti‐SARS‐CoV‐2 immunohistochemistry in six patients and comparison to perniosis before the emergence of SARS‐CoV‐2
Ko CJ, Harigopal M, Damsky W, Gehlhausen JR, Bosenberg M, Patrignelli R, McNiff JM. Perniosis during the COVID‐19 pandemic: Negative anti‐SARS‐CoV‐2 immunohistochemistry in six patients and comparison to perniosis before the emergence of SARS‐CoV‐2. Journal Of Cutaneous Pathology 2020, 47: 997-1002. PMID: 32745281, PMCID: PMC7436569, DOI: 10.1111/cup.13830.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overChilblainsCOVID-19FemaleHumansImmunohistochemistryMaleMiddle AgedSARS-CoV-2ConceptsSARS-CoV-2 nucleocapsid proteinPerivascular lymphocytesImmunohistochemical stainingCOVID-19 pandemicSARS-CoV-2 immunohistochemistryNucleocapsid proteinSARS-CoV-2Inflammatory lesionsHistopathologic findingsIntravascular occlusionMicroscopic findingsPerniosisIntravascular materialLymphocytesLesionsPatientsStainingPandemicSuch casesCuffingHistopathologyCasesImmunohistochemistryFindingsProtein
2019
Visual perception, cognition, and error in dermatologic diagnosis: Key cognitive principles
Ko CJ, Braverman I, Sidlow R, Lowenstein EJ. Visual perception, cognition, and error in dermatologic diagnosis: Key cognitive principles. Journal Of The American Academy Of Dermatology 2019, 81: 1227-1234. PMID: 30797839, DOI: 10.1016/j.jaad.2018.10.082.Peer-Reviewed Original ResearchMeSH KeywordsBiopsy, NeedleCognitionDermatologistsDermatologyDiagnostic ErrorsFemaleHeuristicsHumansImmunohistochemistryMaleSkin DiseasesVisual Perception