1997
Structure of the Trypanosoma brucei U6 snRNA gene promoter
Nakaar V, Günzl A, Ullu E, Tschudi C. Structure of the Trypanosoma brucei U6 snRNA gene promoter. Molecular And Biochemical Parasitology 1997, 88: 13-23. PMID: 9274863, DOI: 10.1016/s0166-6851(97)00078-9.Peer-Reviewed Original ResearchConceptsU6 snRNA gene promoterSnRNA gene promotersB-boxGene promoterA boxSnRNA gene transcriptionInternal control regionRNA polymerase IIITRNA-like genesU6 transcriptionChromatin organizationTranscription extractRNA genesTranscription unitYeast SaccharomycesYeast systemControl regionPolymerase IIIStart siteGene transcriptionNucleotides upstreamPromoter elementsTrypanosoma bruceiIntragenic sequencesSaturation mutagenesis
1994
Upstream tRNA genes are essential for expression of small nuclear and cytoplasmic RNA genes in trypanosomes.
Nakaar V, Dare A, Hong D, Ullu E, Tschudi C. Upstream tRNA genes are essential for expression of small nuclear and cytoplasmic RNA genes in trypanosomes. Molecular And Cellular Biology 1994, 14: 6736-6742. PMID: 7523857, PMCID: PMC359204, DOI: 10.1128/mcb.14.10.6736.Peer-Reviewed Original ResearchConceptsSmall RNA genesTRNA genesRNA genesSmall nuclear RNARegulatory elementsU6 small nuclear RNAUpstream tRNA genesIntragenic promoter elementsT. brucei cellsU6 snRNA genesRNA polymerase IIIB-box elementsSnRNA lociGenome organizationSnRNA genesRNA lociSmall RNAsBrucei cellsB-boxSubstitution mutantsPolymerase IIIFamily TrypanosomatidaeNuclear RNAGene transcriptionPromoter elementsUpstream tRNA genes are essential for expression of small nuclear and cytoplasmic RNA genes in trypanosomes
Nakaar V, Dare A, Hong D, Ullu E, Tschudi C. Upstream tRNA genes are essential for expression of small nuclear and cytoplasmic RNA genes in trypanosomes. Molecular And Cellular Biology 1994, 14: 6736-6742. DOI: 10.1128/mcb.14.10.6736-6742.1994.Peer-Reviewed Original ResearchSmall RNA genesTRNA genesRNA genesSmall nuclear RNARegulatory elementsU6 small nuclear RNAUpstream tRNA genesIntragenic promoter elementsT. brucei cellsU6 snRNA genesRNA polymerase IIIB-box elementsSnRNA lociGenome organizationSnRNA genesRNA lociSmall RNAsBrucei cellsB-boxSubstitution mutantsPolymerase IIIFamily TrypanosomatidaeNuclear RNAGene transcriptionPromoter elementsRNA Polymerase III-Mediated Transcription of the Trypanosome U2 Small Nuclear RNA Gene Is Controlled by both Intragenic and Extragenic Regulatory Elements
Fantoni A, Dare A, Tschudi C. RNA Polymerase III-Mediated Transcription of the Trypanosome U2 Small Nuclear RNA Gene Is Controlled by both Intragenic and Extragenic Regulatory Elements. Molecular And Cellular Biology 1994, 14: 2021-2028. DOI: 10.1128/mcb.14.3.2021-2028.1994.Peer-Reviewed Original ResearchU2 snRNA genesSnRNA genesU2 small nuclear RNA genesSmall nuclear RNA genesRNA polymerase III transcriptionRNA polymerase III-mediated transcriptionCis-acting regulatory sequencesPolymerase III transcriptionRNA polymerase IIIII-mediated transcriptionInternal control regionInsect form trypanosomesTranscription start siteTrimethyl cap structureTRNA genesIII transcriptionPolymerase IIU2 snRNARNA genesStart sitePromoter elementsRegulatory sequencesCoding regionElement transcriptionIntragenic sequencesRNA Polymerase III-Mediated Transcription of the Trypanosome U2 Small Nuclear RNA Gene Is Controlled by both Intragenic and Extragenic Regulatory Elements
Fantoni A, Dare A, Tschudi C. RNA Polymerase III-Mediated Transcription of the Trypanosome U2 Small Nuclear RNA Gene Is Controlled by both Intragenic and Extragenic Regulatory Elements. Molecular And Cellular Biology 1994, 14: 2021-2028. DOI: 10.1128/mcb.14.3.2021-2028.1994.Peer-Reviewed Original ResearchU2 small nuclear RNA genesSmall nuclear RNA genesNuclear RNA genesU2 snRNA genesSnRNA genesRNA genesRNA polymeraseCis-acting regulatory sequencesRNA polymerase III transcriptsInsect form trypanosomesSnRNA gene expressionRNA polymerase IIInternal control regionPolymerase III transcriptsTranscription start siteIII-like enzymeTRNA genesPolymerase IIRegulatory sequencesU2 snRNAControl regionStart siteRegulatory elementsPromoter elementsMutant constructs