Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults
Peno C, Banda D, Jambo N, Kankwatira A, Malamba R, Allain T, Ferreira D, Heyderman R, Russell D, Mwandumba H, Jambo K. Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults. Journal Of Infection 2017, 76: 168-176. PMID: 29197600, PMCID: PMC5792245, DOI: 10.1016/j.jinf.2017.10.013.Peer-Reviewed Original ResearchConceptsT helper 17 responsesCell culture supernatantsAlveolar CD4T cellsAsymptomatic HIVIL-17AT cell immune responsesART-treated HIVART-treated individualsPeripheral blood CD4T-cell countsART-naïve HIVIntracellular cytokine stainingBronchoalveolar lavage fluidCell immune responsesCulture supernatantsBlood CD4Pneumococcal pneumoniaCytokine stainingHIV infectionMalawian adultsLavage fluidHealthy controlsImmune responseAbsolute counts