Niche- and Gender-Dependent Immune Reactions in Relation to the Microbiota Profile in Pediatric Patients with Otitis Media with Effusion
Enoksson F, Rodriguez A, Peno C, Lopez C, Tjernström F, Bogaert D, Hakansson A, Bergenfelz C. Niche- and Gender-Dependent Immune Reactions in Relation to the Microbiota Profile in Pediatric Patients with Otitis Media with Effusion. Infection And Immunity 2020, 88: e00147-20. PMID: 32661126, PMCID: PMC7504947, DOI: 10.1128/iai.00147-20.Peer-Reviewed Original ResearchConceptsMiddle earInflammatory mediatorsOtitis mediaImmune responseChronic low-grade inflammationMiddle ear effusion samplesLow-grade inflammationSpecific inflammatory mediatorsAnti-inflammatory mediatorsAnti-inflammatory profileCommon inflammatory diseaseSigns of infectionHost immune responsePotential pathogenic mechanismsInflammation patternsMale patientsPediatric patientsProinflammatory mediatorsFemale patientsPrecise pathogenesisProinflammatory profileInflammatory diseasesT lymphocytesImmune reactionsPathogenic mechanisms