2019
Guiding Cardiopulmonary Resuscitation with Focused Echocardiography: A Report of Five Cases
Liu R, Bogucki S, Marcolini EG, Yu CY, Wira CR, Kalam S, Daley J, Moore CL, Cone D. Guiding Cardiopulmonary Resuscitation with Focused Echocardiography: A Report of Five Cases. Prehospital Emergency Care 2019, 24: 297-302. PMID: 31150302, DOI: 10.1080/10903127.2019.1626955.Peer-Reviewed Original ResearchConceptsCardiopulmonary resuscitationCardiac arrestEchocardiography studyFocused echocardiographyAdvanced cardiac life support algorithmLeft ventricular compressionCardiac arrest patientsEnd-tidal carbon dioxide valuesHospital cardiac arrestTransthoracic echocardiography studyFocused transthoracic echocardiographyTidal carbon dioxide valuesTransthoracic echocardiographyVentricular compressionArrest patientsPatient outcomesHemodynamic parametersPulse checksEchocardiographyInadequate compressionResuscitationCarbon dioxide valuesUltrasound timingPhysical performanceUltrasound performance
2016
When to Stop CPR and When to Perform Rhythm Analysis
Giberson B, Uber A, Gaieski D, Miller JB, Wira C, Berg K, Giberson T, Cocchi MN, Abella B, Donnino MW. When to Stop CPR and When to Perform Rhythm Analysis. Journal Of Intensive Care Medicine 2016, 31: 537-543. PMID: 25542192, DOI: 10.1177/0885066614561589.Peer-Reviewed Original ResearchConceptsAdvanced cardiac life supportMajority of respondersUrban tertiary care centerTertiary care centerMinutes of CPRUninterrupted chest compressionsCardiac arrest managementCardiac life supportHealth care providersAdditional therapyCardiac medicationsPalpable pulseRhythm checkCardiac arrestCare centerObservational studyPulse checksCare providersChest compressionsACLS algorithmsResponse rateACLS certificationAdult staff membersMedical providersWeb-based survey
2015
Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome
Sivaraju A, Gilmore EJ, Wira CR, Stevens A, Rampal N, Moeller JJ, Greer DM, Hirsch LJ, Gaspard N. Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome. Intensive Care Medicine 2015, 41: 1264-1272. PMID: 25940963, DOI: 10.1007/s00134-015-3834-x.Peer-Reviewed Original ResearchConceptsBetter outcomesPoor outcomeEpileptiform dischargesPost-cardiac arrest comatose patientsCritical care EEG terminologyPost-cardiac arrest comaMethodsProspective cohort studyContinuous EEG monitoringLow-voltage EEGPositive predictive valueAbsence of reactivityEEG terminologyCohort studySpontaneous circulationBrainstem reflexesClinical outcomesComatose patientsFalse positive ratePoor prognosisPrognostic significanceSuppression burstsClinical variablesClinical correlatesElectroencephalographic patternsElectroencephalographic predictors
2007
Effective lactate clearance is associated with improved outcome in post-cardiac arrest patients
Donnino MW, Miller J, Goyal N, Loomba M, Sankey SS, Dolcourt B, Sherwin R, Otero R, Wira C. Effective lactate clearance is associated with improved outcome in post-cardiac arrest patients. Resuscitation 2007, 75: 229-234. PMID: 17583412, DOI: 10.1016/j.resuscitation.2007.03.021.Peer-Reviewed Original ResearchConceptsPost-cardiac arrest patientsHigher lactate clearanceArrest patientsLactate clearanceAPACHE II scoreCardiac arrest patientsInitial lactate levelUrban emergency departmentPre-hospital providersEmergency medical servicesHospital mortalityTraumatic arrestHospital courseHospital survivalII scorePrimary endpointHospital dischargeImproved mortalityOverall mortalityMean lactateMultivariable analysisSuccessful resuscitationCardiac arrestEmergency departmentMean age
2006
Application of normothermic cardiac arrest algorithms to hypothermic cardiac arrest in a canine model
Wira C, Martin G, Stoner J, Margolis K, Donnino M. Application of normothermic cardiac arrest algorithms to hypothermic cardiac arrest in a canine model. Resuscitation 2006, 69: 509-516. PMID: 16597482, DOI: 10.1016/j.resuscitation.2005.10.028.Peer-Reviewed Original Research