2024
The Impact of Preprocedural Platelet Function Testing on Periprocedural Complication Rates Associated With Pipeline Flow Diversion: An International Multicenter Study
Vranic J, Dmytriw A, Berglar I, Alotaibi N, Cancelliere N, Stapleton C, Rabinov J, Harker P, Gupta R, Bernstock J, Koch M, Raymond S, Mascitelli J, Patterson T, Seinfeld J, White A, Case D, Roark C, Gandhi C, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia D, Ocampo-Navia M, Villamizar-Torres D, Puentes J, Salem M, Baig A, Namaani K, Kühn A, Pukenas B, Jankowitz B, Burkhardt J, Siddiqui A, Jabbour P, Singh J, Puri A, Regenhardt R, Pereira V, Patel A. The Impact of Preprocedural Platelet Function Testing on Periprocedural Complication Rates Associated With Pipeline Flow Diversion: An International Multicenter Study. Neurosurgery 2024, 95: 179-185. PMID: 38634693, DOI: 10.1227/neu.0000000000002956.Peer-Reviewed Original ResearchPlatelet function testsPipeline Embolization DeviceDual antiplatelet therapyGroup patientsIntracranial complicationsDAPT regimenThromboembolic complicationsPED treatment of intracranial aneurysmsResults of platelet function testingPipeline Embolization Device embolizationPipeline Embolization Device treatmentFunction testsIntracranial aneurysmsPipeline flow diversionPermanent neurological disabilityInternational multicenter studyFlow diversionTreatment of intracranial aneurysmsUnruptured intracranial aneurysmsWilcoxon rank-sumClopidogrel nonrespondersComplication rateMulticenter studyAntiplatelet therapyFisher's exact308 Improvement in Cranial Nerve Neuropathies Following Treatment of Intracranial Aneurysms With Flow Diverters: Institutional Outcomes and Meta-analysis of Literature
Sujijantarat N, Antonios J, Koo A, Haynes J, Renedo D, Hebert R, Sheth K, King J, Matouk C. 308 Improvement in Cranial Nerve Neuropathies Following Treatment of Intracranial Aneurysms With Flow Diverters: Institutional Outcomes and Meta-analysis of Literature. Neurosurgery 2024, 70: 89-89. DOI: 10.1227/neu.0000000000002809_308.Peer-Reviewed Original ResearchIntracranial aneurysmsPooled rateMeta-analysisCranial nervesRate of clinical improvementNear total occlusionAneurysms treated with flow diversionCranial nerve neuropathyMonths of presentationFlow diversionAssociated with symptomatic improvementRare presenting symptomSymptomatic intracranial aneurysmsRate of improvementTreatment of intracranial aneurysmsRandom-effects meta-analysisMeta-analysis of literatureEffects meta-analysisOphthalmological outcomesCN deficitsRetrospective reviewAssociated with improvementsClinical improvementNerve neuropathySymptomatic improvement
2023
The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study
Vranic J, Harker P, Stapleton C, Regenhardt R, Dmytriw A, Doron O, Alotaibi N, Leslie-Mazwi T, Gupta R, Berglar I, Tan C, Koch M, Raymond S, Mascitelli J, Patterson T, Seinfeld J, White A, Case D, Roark C, Gandhi C, Al-Mufti F, Cooper J, Matouk C, Sujijantarat N, Devia D, Ocampo-Navia M, Villamizar-Torres D, Puentes J, Patel A. The Impact of Dual Antiplatelet Therapy Duration on Unruptured Aneurysm Occlusion After Flow Diversion: A Multicenter Study. Journal Of Computer Assisted Tomography 2023, 47: 753-758. PMID: 37707405, DOI: 10.1097/rct.0000000000001457.Peer-Reviewed Original ResearchConceptsDual antiplatelet therapyAneurysm occlusion rateAneurysm occlusionDAPT durationThromboembolic complicationsOcclusion rateFlow diversionDuration of DAPTDual antiplatelet therapy durationIntracranial aneurysmsSingle Pipeline Embolization DeviceAntiplatelet therapy durationEndoluminal flow diversionRate of complicationsPrimary outcome measurePipeline Embolization DeviceSignificant differencesUnruptured intracranial aneurysmsAspirin monotherapyAntiplatelet therapyIschemic strokeTherapy durationIatrogenic complicationsRetrospective reviewMulticenter study482 Triple Therapy Versus Dual Antiplatelet Therapy for Dolichoectatic Vertebrobasilar Fusiform Aneurysms Treated With Flow Diverters: The Last Frontier?
Siddiqui A, Monteiro A, Hanel R, Kan P, Mohanty A, Cortez G, Rabinovich M, Matouk C, Sujijantarat N, Romero C, Stone J, Ebersole K, Fry L, Natarajan S, Thomson B, Ortega-Gutierrez S, Vivanco-Suarez J, Wakhloo A, Levy E. 482 Triple Therapy Versus Dual Antiplatelet Therapy for Dolichoectatic Vertebrobasilar Fusiform Aneurysms Treated With Flow Diverters: The Last Frontier? Neurosurgery 2023, 69: 103-104. DOI: 10.1227/neu.0000000000002375_482.Peer-Reviewed Original ResearchTriple therapy groupDual antiplatelet therapyVertebrobasilar fusiform aneurysmsBrainstem compressionIschemic strokeAneurysm characteristicsFusiform aneurysmsFlow diversionIschemic stroke ratePoor natural historyRetrospective data collectionOverall rateAntiplatelet therapyBaseline disabilityHemorrhagic complicationsRadial access useTriple therapyAngiographic outcomesClinical outcomesClinical presentationHigh morbimortalityAdjunctive coilingSimilar patientsMedian numberPerforator occlusion
2017
O-018 Flow diversion for the treatment of basilar apex aneurysms
Dmytriw, Adeeb N, Kumar A, Griessenauer C, Ogilvy C, Foreman P, Shallwani H, Limbucci N, Mangiafico S, Michelozzi C, Krings T, Pereira V, Matouk C, Zhang Y, Harrigan M, Phan K, Shakir H, Siqqiqui A, Levy E, Renieri L, Cognard C, Thomas A, Marotta T. O-018 Flow diversion for the treatment of basilar apex aneurysms. Journal Of NeuroInterventional Surgery 2017, 9: a11. DOI: 10.1136/neurintsurg-2017-snis.18.Peer-Reviewed Original ResearchBasilar apex aneurysmsPosterior circulation aneurysmsComplication rateFlow diversionCommon off-label useHigh complication rateAneurysmal subarachnoid hemorrhageOff-label useSignificant treatment challengePipeline Embolization DeviceRedirection Endoluminal DeviceSingle flow diverterPostprocedural settingSymptomatic thromboembolicHemorrhagic complicationsMinor complicationsNeurologic deficitsConsecutive patientsMajor complicationsAdditional patientsRetrospective reviewAdjunctive coilingSubarachnoid hemorrhagePED placementCerebellar stroke