2024
The impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction
Hazan H, Ferrara M, Riley S, Li F, Zhou B, Kline E, Gibbs-Dean T, Karmani S, Tayfur S, Tek C, Keshavan M, Srihari V. The impact of early detection (ED) campaigns on care presentations: Beyond DUP reduction. Schizophrenia Research 2024, 264: 457-461. PMID: 38266513, PMCID: PMC10923115, DOI: 10.1016/j.schres.2024.01.022.Peer-Reviewed Original ResearchConceptsCoordinated specialty careDuration of untreated psychosisImpact of early detectionEarly detectionEarly detection campaignsSpecialty careAdjustment scoresCampaign yearDetection campaignsMediation analysisEffects of EDRegression modelsCareUntreated psychosisPositive symptomsGAFPatientsSalutary effects
2023
The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service
Ferrara M, Guloksuz S, Hazan H, Li F, Tek C, Sykes L, Riley S, Keshavan M, Srihari V. The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service. Schizophrenia Research 2023, 260: 198-204. PMID: 37688984, DOI: 10.1016/j.schres.2023.08.005.Peer-Reviewed Original ResearchConceptsFirst-episode psychosis servicesLength of stayUntreated psychosisPsychiatric hospitalizationFirst-episode servicesDuration of hospitalizationIncidence rate ratiosNon-affective psychosisNew Haven areaPoisson regression modelsPatient characteristicsHospitalization ratesRecent onsetMedical recordsHospitalizationEffect of durationNegative binomial regressionSpecialized treatmentPsychosisRate ratioBinomial regressionAdmissionDUPEnrollmentFirst year
2017
Alpha‐lipoic acid (ALA) as a supplementation for weight loss: results from a meta‐analysis of randomized controlled trials
Kucukgoncu S, Zhou E, Lucas K, Tek C. Alpha‐lipoic acid (ALA) as a supplementation for weight loss: results from a meta‐analysis of randomized controlled trials. Obesity Reviews 2017, 18: 594-601. PMID: 28295905, PMCID: PMC5523816, DOI: 10.1111/obr.12528.Peer-Reviewed Original ResearchConceptsAlpha-lipoic acidBody mass indexAlpha-lipoic acid treatmentPlacebo groupWeight lossEffect of ALASignificant short-term weight lossShort-term weight lossModest weight lossPlacebo treatment groupsPlacebo-controlled studyWeight changeAnti-obesity propertiesSystematic literature searchMeta-regression analysisMass indexSignificant morbidityALA doseBMI changeLong-term benefitsWeight managementBMI differencesTreatment groupsMortality rateStudy duration
2009
The unchanging mortality gap for people with schizophrenia
Chwastiak LA, Tek C. The unchanging mortality gap for people with schizophrenia. The Lancet 2009, 374: 590-592. PMID: 19595448, DOI: 10.1016/s0140-6736(09)61072-2.Peer-Reviewed Original Research
2007
A pilot study of a weight management program with food provision in schizophrenia
Jean-Baptiste M, Tek C, Liskov E, Chakunta UR, Nicholls S, Hassan AQ, Brownell KD, Wexler BE. A pilot study of a weight management program with food provision in schizophrenia. Schizophrenia Research 2007, 96: 198-205. PMID: 17628437, DOI: 10.1016/j.schres.2007.05.022.Peer-Reviewed Original ResearchConceptsWeight lossSignificant medical risksMeaningful weight lossWeight loss programWeight management programSevere mental illnessSerious medical problemLifestyle modificationComorbid obesityLoss programPilot trialGeneral populationMetabolic indicesCognitive impairmentMental illnessMedical riskMedical problemsWeight gainObesityPilot studySpecific populationsSchizophreniaBehavioral programHealthy foodsReplacement program
2003
Letter to the editor. Substance abuse and the heterogeneity of schizophrenia a population-based study
Messias E, Tek C, Kirkpatrick B. Letter to the editor. Substance abuse and the heterogeneity of schizophrenia a population-based study. Schizophrenia Research 2003, 62: 293-294. PMID: 12837529, DOI: 10.1016/s0920-9964(02)00212-8.Peer-Reviewed Original Research
2002
Visual Perceptual and Working Memory Impairments in Schizophrenia
Tek C, Gold J, Blaxton T, Wilk C, McMahon RP, Buchanan RW. Visual Perceptual and Working Memory Impairments in Schizophrenia. JAMA Psychiatry 2002, 59: 146-153. PMID: 11825136, DOI: 10.1001/archpsyc.59.2.146.Peer-Reviewed Original ResearchConceptsMemory testPerceptual discriminationPerceptual impairmentsImpaired performanceMemory impairmentVisual perceptual discriminationVisual working memoryPerceptual discrimination taskVisual perceptual processingVisual perceptual impairmentsPosterior brain areasWorking Memory ImpairmentSpatial visual perceptionVisual information processingSpatial visual informationPerceptual processingWorking memoryVisual perceptualPerceptual systemDiscrimination taskVisual perceptionVisual stimuliActive maintenanceSpatial testsExtent of impairment
2001
Religiosity and religious obsessions in obsessive–compulsive disorder
Tek C, Ulug B. Religiosity and religious obsessions in obsessive–compulsive disorder. Psychiatry Research 2001, 104: 99-108. PMID: 11711164, DOI: 10.1016/s0165-1781(01)00310-9.Peer-Reviewed Original ResearchSummer Birth and Deficit Schizophrenia in Nithsdale, Scotland
TEK C, KIRKPATRICK B, KELLY C, MCCREADIE R. Summer Birth and Deficit Schizophrenia in Nithsdale, Scotland. The Journal Of Nervous And Mental Disease 2001, 189: 613-617. PMID: 11580005, DOI: 10.1097/00005053-200109000-00007.Peer-Reviewed Original ResearchA five-year followup study of deficit and nondeficit schizophrenia
Tek C, Kirkpatrick B, Buchanan RW. A five-year followup study of deficit and nondeficit schizophrenia. Schizophrenia Research 2001, 49: 253-260. PMID: 11356586, DOI: 10.1016/s0920-9964(00)00146-8.Peer-Reviewed Original ResearchConceptsDeficit schizophreniaClinical featuresNondeficit schizophreniaDeficit patientsDeficit/nondeficit categorizationNegative symptomsStable clinical featuresSevere negative symptomsQuality of lifeBaseline negative symptomsPoor outcomeIll outpatientsYear followupFollowup assessmentsSevere hallucinationsFollowup studyPsychosocial functionPatientsOccupational functionFollowupStable subtypeSchizophreniaThought disorderOutpatientsSymptoms
1995
Yale‐Brown Obsessive Compulsive Scale and US National Institute of Mental Health Global Obsessive Compulsive Scale in Turkish: reliability and validity
Tek C, Uluǧ B, Rezaki B, Tanriverdi N, Mercan S, Demir B, Vargel S. Yale‐Brown Obsessive Compulsive Scale and US National Institute of Mental Health Global Obsessive Compulsive Scale in Turkish: reliability and validity. Acta Psychiatrica Scandinavica 1995, 91: 410-413. PMID: 7676839, DOI: 10.1111/j.1600-0447.1995.tb09801.x.Peer-Reviewed Original Research