1995
Cloning of a bovine renal epithelial Na+ channel subunit
Fuller C, Awayda M, Arrate M, Bradford A, Morris R, Canessa C, Rossier B, Benos D. Cloning of a bovine renal epithelial Na+ channel subunit. American Journal Of Physiology 1995, 269: c641-c654. PMID: 7573394, DOI: 10.1152/ajpcell.1995.269.3.c641.Peer-Reviewed Original ResearchConceptsChannel subunitsOpen reading frameProtein kinase A.Gamma-ENaC subunitsCDNA expression libraryProtein kinase CVitro translationCDNA clonesBovine cDNAXenopus laevis oocytesPancreatic microsomesAcid proteinReading frameNovel isoformBovine homologueExpression libraryConsensus sequenceKinase CBase pairsAlpha-hENaCXenopus oocytesChimeric channelsHuman counterpartLaevis oocytesSubunits
1993
The Epithelial Sodium Channel: Recent Developments
Horisberger J, Canessa C, Rossier B. The Epithelial Sodium Channel: Recent Developments. Cellular Physiology And Biochemistry 1993, 3: 283-294. DOI: 10.1159/000154694.Peer-Reviewed Original ResearchApical membraneLarge protein complexesPutative transmembrane segmentsNew channel proteinsAmino acid sequenceSingle cDNA cloneProtein kinase CNematode CaenorhabditisProtein complexesTransmembrane segmentsCDNA clonesAcid sequenceEpithelial sodium channelPotential subunitsChannel proteinsKinase CG proteinsCell deathNeuronal cell deathSensory transductionIntracellular factorsCation channelsMembrane ionic permeabilityAmiloride-sensitive channelsGenes