2021
Strategies to Minimize Iodinated Contrast Volume in Patients with Chronic Kidney Disease Undergoing Peripheral Vascular Interventions
Lee SR, Dardik A, Chaar CIO. Strategies to Minimize Iodinated Contrast Volume in Patients with Chronic Kidney Disease Undergoing Peripheral Vascular Interventions. Annals Of Vascular Surgery 2021, 73: 490-495. PMID: 33556507, DOI: 10.1016/j.avsg.2021.01.081.Peer-Reviewed Original ResearchConceptsPeripheral vascular interventionsChronic kidney diseaseVascular interventionsPostcontrast acute kidney injuryChronic limb threatening ischemiaSuccessful endovascular revascularizationAcute kidney injuryCKD stage 4Limb threatening ischemiaPC-AKIEndovascular revascularizationKidney injuryUse of ICMContrast volumeKidney diseaseIntravascular lesionsContrast mediumPatientsStage 4InterventionRiskRevascularizationIschemiaInjuryTherapy
2020
Regional Anesthesia is Underutilized for Carotid Endarterectomy Despite Improved Perioperative Outcomes Compared with General Anesthesia
Lumas S, Hsiang W, Akhtar S, Ochoa Chaar CI. Regional Anesthesia is Underutilized for Carotid Endarterectomy Despite Improved Perioperative Outcomes Compared with General Anesthesia. Annals Of Vascular Surgery 2020, 73: 336-343. PMID: 33373769, DOI: 10.1016/j.avsg.2020.11.035.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramCarotid endarterectomyGeneral anesthesiaRegional anesthesiaImproved outcomesSurgeons National Surgical Quality Improvement ProgramChronic obstructive pulmonary diseaseOutcomes of CEASurgical Quality Improvement ProgramCombined end pointObstructive pulmonary diseaseChoice of anestheticQuality Improvement ProgramAnesthesia typeHospital lengthPerioperative outcomesBaseline characteristicsPatient characteristicsCarotid surgeryHeart failurePropensity matchingPulmonary diseaseGA patientsMyocardial infarctionAmerican CollegeOutcomes of treatment with paclitaxel-coated devices for peripheral arterial disease
Kim TI, Kiwan G, Mohamedali A, Zhang Y, Mena-Hurtado C, Mojibian H, Guzman RJ, Ochoa Chaar CI. Outcomes of treatment with paclitaxel-coated devices for peripheral arterial disease. Journal Of Vascular Surgery 2020, 73: 911-917. PMID: 33038480, DOI: 10.1016/j.jvs.2020.08.146.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmputation, SurgicalCardiovascular AgentsCoated Materials, BiocompatibleDrug-Eluting StentsEndovascular ProceduresFemaleHumansLimb SalvageMaleMiddle AgedPaclitaxelPeripheral Arterial DiseaseProsthesis DesignRetreatmentRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular PatencyConceptsPaclitaxel-coated devicesPeripheral artery diseaseCause of mortalityPCD useRisk of mortalityCumulative doseFemoropopliteal peripheral artery diseaseKaplan-Meier survival curvesLong-term mortalityPeripheral arterial diseaseCox regression analysisDrug-coated balloonsOutcome of treatmentDrug-eluting stentsMajor amputationPrimary patencyReintervention rateArtery diseaseArterial diseaseRandomized trialsOpen surgeryPresent studySingle institutionEndovascular interventionPatientsLower Extremity Revascularization for Chronic Limb-Threatening Ischemia among Patients at the Extremes of Age
Kim TI, Aboian E, Fischer U, Zhang Y, Guzman RJ, Ochoa Chaar CI. Lower Extremity Revascularization for Chronic Limb-Threatening Ischemia among Patients at the Extremes of Age. Annals Of Vascular Surgery 2020, 72: 517-528. PMID: 32927042, DOI: 10.1016/j.avsg.2020.08.135.Peer-Reviewed Original ResearchMeSH KeywordsAge of OnsetAgedAged, 80 and overAgingAmputation, SurgicalChronic DiseaseDatabases, FactualEndovascular ProceduresFemaleHumansIschemiaLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseaseRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsChronic limb-threatening ischemiaLower extremity revascularizationExtremes of ageRisk factor profileMajor amputationPatients 51Extremity revascularizationFactor profileDistinct risk factor profilesAge groupsChronic limb threatening ischemiaLimb threatening ischemiaLimb-threatening ischemiaMajor amputation ratePeripheral artery diseaseGroup of patientsInsulin-dependent diabetesExtreme age groupsSuprainguinal bypassAmputation rateElderly patientsInfrainguinal bypassActive smokersArtery diseaseMultivariable analysisTrends and outcomes of thoracic endovascular aortic repair with open concomitant cervical debranching
Bellamkonda KS, Yousef S, Nassiri N, Dardik A, Guzman RJ, Geirsson A, Ochoa Chaar CI. Trends and outcomes of thoracic endovascular aortic repair with open concomitant cervical debranching. Journal Of Vascular Surgery 2020, 73: 1205-1212.e3. PMID: 32861861, DOI: 10.1016/j.jvs.2020.07.103.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAorta, ThoracicAortic DiseasesBlood Vessel Prosthesis ImplantationCarotid ArteriesDatabases, FactualEndovascular ProceduresFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsSubclavian ArteryTime FactorsTreatment OutcomeYoung AdultConceptsCarotid-carotid bypassEndovascular aortic repairCervical debranchingPerioperative outcomesAortic repairAortic pathologyMultivariable analysisThoracic endovascular aortic repairSurgeons National Surgical Quality Improvement Program filesCarotid-subclavian bypassDependent functional statusOpen surgical debranchingUse of TEVARLonger hospital stayCurrent Procedural Terminology codesUrgency of surgeryComplex aortic pathologiesThoracic aortic pathologyCommon surgical procedureProcedural Terminology codesSignificant differencesNumber of bypassesAdvanced endovascular technologySurgical debranchingDebranching proceduresEndograft type and anesthesia mode are associated with mortality of endovascular aneurysm repair for ruptured abdominal aortic aneurysms
Bellamkonda KS, Yousef S, Zhang Y, Dardik A, Geirsson A, Chaar CIO. Endograft type and anesthesia mode are associated with mortality of endovascular aneurysm repair for ruptured abdominal aortic aneurysms. Vascular 2020, 29: 155-162. PMID: 32787557, DOI: 10.1177/1708538120947859.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnesthesia, GeneralAortic Aneurysm, AbdominalAortic RuptureBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationDatabases, FactualEndovascular ProceduresFemaleHumansMaleMiddle AgedProsthesis DesignRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeYoung AdultConceptsInfrarenal abdominal aortic aneurysmAbdominal aortic aneurysmEndovascular aneurysm repairBody mass indexAortic aneurysmEndograft typeAneurysm repairOverall mortalityMass indexSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseRuptured infrarenal abdominal aortic aneurysmQuality Improvement Program databaseRuptured abdominal aortic aneurysmLower body mass indexAbdominal aortic aneurysm diameterAneurysmal iliac arteriesDependent functional statusCharacteristics of patientsImprovement Program databasePrimary treatment modalityOpen abdominal surgeryAortic aneurysm diameterSignificant differencesConcomitant stentingComparison of Atherectomy to Balloon Angioplasty and Stenting for Isolated Femoropopliteal Revascularization
Bai H, Fereydooni A, Zhuo H, Zhang Y, Tonnessen B, Guzman RJ, Ochoa Chaar CI. Comparison of Atherectomy to Balloon Angioplasty and Stenting for Isolated Femoropopliteal Revascularization. Annals Of Vascular Surgery 2020, 69: 261-273. PMID: 32512112, DOI: 10.1016/j.avsg.2020.05.019.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal angioplastyMajor ipsilateral amputationIpsilateral amputationPrimary patencyDistal embolizationFemoropopliteal diseaseBalloon angioplastyTechnical successStatus improvementAnkle-brachial index improvementSignificant additional clinical benefitSociety Consensus (TASC) II classificationChronic obstructive pulmonary diseaseConcomitant open surgeryLower ratesOutcomes of atherectomyUse of atherectomyAcute limb ischemiaOne-year outcomesVascular Quality InitiativeCongestive heart failureHigher reintervention rateLower extremity revascularizationObstructive pulmonary diseaseAdditional clinical benefitThe Reintervention Index: A New Outcome Measure for Comparative Effectiveness of Lower Extremity Revascularization
Ochoa Chaar CI, Gholitabar N, DeTrani M, Jorshery S, Zhuo H, Zhang Y, Dardik A. The Reintervention Index: A New Outcome Measure for Comparative Effectiveness of Lower Extremity Revascularization. Annals Of Vascular Surgery 2020, 69: 52-61. PMID: 32474144, DOI: 10.1016/j.avsg.2020.05.040.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmputation, SurgicalComparative Effectiveness ResearchEndarterectomyEndovascular ProceduresFemaleHumansLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseasePostoperative ComplicationsRetreatmentRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular GraftingConceptsOpen lower extremity revascularizationLower extremity revascularizationPeripheral artery diseaseEndovascular groupExtremity revascularizationOutcome measuresEndovascular lower extremity revascularizationFrequency of reinterventionsTertiary care centerCurrent outcome measuresNew outcome measureType of procedureCardiovascular comorbiditiesMajor amputationEndovascular revascularizationReintervention ratePatient characteristicsArtery diseaseConsecutive patientsMultivariable analysisRetrospective reviewOpen groupCare centerEndovascular proceduresReinterventionTrends of hospital-based surgery for varicose veins in the elderly
Kim TI, Zhang Y, Guzman RJ, Ochoa Chaar CI. Trends of hospital-based surgery for varicose veins in the elderly. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2020, 9: 146-153.e2. PMID: 32360785, DOI: 10.1016/j.jvsv.2020.04.016.Peer-Reviewed Original ResearchMeSH KeywordsAblation TechniquesAge FactorsAgedAged, 80 and overAnesthesia, GeneralDatabases, FactualFemaleHospitalizationHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVaricose VeinsVascular Surgical ProceduresVenous InsufficiencyConceptsProportion of patientsAdverse eventsVenous ablationGeneral anesthesiaVaricose veinsAge groupsVein ablationVein surgeryHospital-based surgeryCurrent Procedural Terminology codesHigh-risk patientsVaricose vein surgeryProcedural Terminology codesLarge national databaseYounger age groupsPaucity of dataMore comorbiditiesAnesthesiologists classificationOverall morbidityVenous surgeryDialysis populationVenous insufficiencyOpen surgeryConservative measuresOperative characteristicsPresentation and outcomes of carotid endarterectomy in active smokers
Kim TI, Zhang Y, Amin HP, Ochoa Chaar CI. Presentation and outcomes of carotid endarterectomy in active smokers. Journal Of Vascular Surgery 2020, 72: 1720-1727.e1. PMID: 32249043, DOI: 10.1016/j.jvs.2020.02.014.Peer-Reviewed Original ResearchConceptsCarotid endarterectomyRisk factorsWorse outcomesSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramChronic obstructive pulmonary diseaseSignificant modifiable risk factorSurgical Quality Improvement ProgramHigh anatomic riskOutcomes of patientsModifiable risk factorsObstructive pulmonary diseaseCarotid artery diseaseImportant risk factorLarge national databaseQuality Improvement ProgramActive smokingEmergent surgeryPreoperative characteristicsActive smokersArtery diseasePropensity matchingPulmonary diseaseSymptomatic presentationSmoking statusReply
Aurshina A, Ochoa Chaar CI. Reply. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2020, 8: 337-338. PMID: 32067734, DOI: 10.1016/j.jvsv.2019.11.005.Peer-Reviewed Original Research
2019
Perioperative Outcomes of Lower Extremity Revascularization for Rest Pain and Tissue Loss
Tsay C, Luo J, Zhang Y, Attaran R, Dardik A, Ochoa Chaar CI. Perioperative Outcomes of Lower Extremity Revascularization for Rest Pain and Tissue Loss. Annals Of Vascular Surgery 2019, 66: 493-501. PMID: 31756416, DOI: 10.1016/j.avsg.2019.11.019.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAmputation, SurgicalCritical IllnessDatabases, FactualFemaleGangreneHumansIschemiaLeg UlcerLength of StayLimb SalvageLower ExtremityMaleMiddle AgedPainPatient ReadmissionPeripheral Arterial DiseasePostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeUnited StatesVascular GraftingYoung AdultConceptsCritical limb ischemiaRest painMajor amputationTissue lossPerioperative outcomesTL patientsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseSevere peripheral artery diseaseQuality Improvement Program databaseTerms of pneumoniaWorse perioperative outcomesLonger hospital stayHigher American SocietyImprovement Program databasePeripheral artery diseaseCongestive heart failureLower Extremity RevascularizationICD-10 codesAnesthesiologists classUnplanned intubationHospital stayPerioperative mortalityExtremity revascularizationLimb ischemiaNational trends of hybrid lower extremity revascularization in the ACS-NSQIP database
Fereydooni A, Zhou B, Jorshery SD, Deng Y, Dardik A, Chaar CIO. National trends of hybrid lower extremity revascularization in the ACS-NSQIP database. Vascular 2019, 27: 653-662. PMID: 31126228, DOI: 10.1177/1708538119852019.Peer-Reviewed Original ResearchConceptsLower extremity revascularizationExtremity revascularizationPeripheral artery diseaseVascular surgeonsSurgical specialistsPerioperative outcomesArtery diseaseHybrid surgeryHybrid procedureNational Surgical Quality Improvement Project databaseSurgeons National Surgical Quality Improvement Project databaseDisease codes -9Non-vascular surgeonsCurrent Procedural Terminology codesACS-NSQIP databaseProcedural Terminology codesNational trendsContemporary national trendsAnesthesiologists classificationEmergent surgeryOverall morbidityOnly patientsFemoral endarterectomyPropensity matchingStatin therapy associated with improved thrombus resolution in patients with deep vein thrombosis
Hsu C, Brahmandam A, Brownson KE, Huynh N, Reynolds J, Lee AI, Fares WH, Ochoa Chaar CI. Statin therapy associated with improved thrombus resolution in patients with deep vein thrombosis. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2019, 7: 169-175.e4. PMID: 30660579, DOI: 10.1016/j.jvsv.2018.10.020.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnticoagulantsElectronic Health RecordsFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedPlatelet Aggregation InhibitorsPulmonary EmbolismRecurrenceRetrospective StudiesRisk AssessmentRisk FactorsThrombolytic TherapyTime FactorsTreatment OutcomeVena Cava FiltersVenous ThromboembolismVenous ThrombosisConceptsDeep venous thrombosisExtent of DVTStatin therapyThrombus resolutionPulmonary embolismVenous thromboembolismVTE recurrenceAntiplatelet therapyMultivariable analysisRisk factorsRecurrence of DVTLower extremity deep venous thrombosisHigh-risk pulmonary embolismPrior deep venous thrombosisProvoked deep venous thrombosisProximal deep venous thrombosisInferior vena cava filter placementExtremity deep venous thrombosisVena cava filter placementDuration of anticoagulationAssociation of statinConsecutive adult patientsDirect oral anticoagulantsManifestations of atherosclerosisCava filter placement
2015
Management of isolated calf vein thrombosis in cancer patients
Brahmandam AS, Brownson K, Skrip L, Parker T, Indes J, Sarac T, Dardik A, Chaar CI. Management of isolated calf vein thrombosis in cancer patients. Vascular 2015, 24: 64-69. PMID: 25957344, DOI: 10.1177/1708538115584726.Peer-Reviewed Original ResearchConceptsCalf vein thrombosisIsolated calf vein thrombosisVein thrombosisHistory of cancerCancer patientsBenefits of anticoagulationInitiation of anticoagulationPatient risk factorsRetrospective chart reviewLong-term recurrenceChart reviewConsecutive patientsTreatment modalitiesRisk factorsThrombosisHigh incidencePatientsAnticoagulationOlder ageCancerMortalityIncidenceAnatomical characteristicsTreatmentRecurrence