2023
Clinical trial data sharing: a cross-sectional study of outcomes associated with two U.S. National Institutes of Health models
Rowhani-Farid A, Grewal M, Solar S, Eghrari A, Zhang A, Gross C, Krumholz H, Ross J. Clinical trial data sharing: a cross-sectional study of outcomes associated with two U.S. National Institutes of Health models. Scientific Data 2023, 10: 529. PMID: 37553403, PMCID: PMC10409750, DOI: 10.1038/s41597-023-02436-0.Peer-Reviewed Original ResearchMeSH KeywordsClinical Trials as TopicCross-Sectional StudiesInformation DisseminationNational Cancer Institute (U.S.)National Institutes of Health (U.S.)United StatesParent Priorities in End-of-Life Care for Children With Cancer
Ananth P, Lindsay M, Mun S, McCollum S, Shabanova V, de Oliveira S, Pitafi S, Kirch R, Ma X, Gross C, Boyden J, Feudtner C, Wolfe J. Parent Priorities in End-of-Life Care for Children With Cancer. JAMA Network Open 2023, 6: e2313503. PMID: 37184834, PMCID: PMC10878399, DOI: 10.1001/jamanetworkopen.2023.13503.Peer-Reviewed Original Research
2021
Clinical trial transparency and data sharing among biopharmaceutical companies and the role of company size, location and product type: a cross-sectional descriptive analysis
Axson S, Mello MM, Lincow D, Yang C, Gross C, Ross JS, Miller J. Clinical trial transparency and data sharing among biopharmaceutical companies and the role of company size, location and product type: a cross-sectional descriptive analysis. BMJ Open 2021, 11: e053248. PMID: 34281933, PMCID: PMC8291313, DOI: 10.1136/bmjopen-2021-053248.Peer-Reviewed Original ResearchMeSH KeywordsBiological ProductsCross-Sectional StudiesDrug ApprovalHumansInformation DisseminationUnited StatesUnited States Food and Drug AdministrationAssociation Between Sexual Orientation, Mistreatment, and Burnout Among US Medical Students
Samuels EA, Boatright DH, Wong AH, Cramer LD, Desai MM, Solotke MT, Latimore D, Gross CP. Association Between Sexual Orientation, Mistreatment, and Burnout Among US Medical Students. JAMA Network Open 2021, 4: e2036136. PMID: 33528552, PMCID: PMC7856540, DOI: 10.1001/jamanetworkopen.2020.36136.Peer-Reviewed Original ResearchConceptsOdds of burnoutAAMC Graduation QuestionnaireMedical studentsSexual orientationAssociated with increased odds of burnoutGraduation QuestionnaireMedical schoolsPoor quality careHeterosexual studentsProbability of burnoutFear of discriminationUS allopathic medical schoolsAssociated with increased oddsExperiences of mistreatmentUS medical studentsAllopathic medical schoolsCross-sectional studyMedical student burnoutLogistic regression modelsSexual minority groupsQuality careOldenburg Burnout Inventory for Medical StudentsLGB sexual orientationTrainee burnoutMain Outcomes
2020
Is there variation in private payor payments to cancer surgeons? A cross-sectional study in the USA
Bongiovanni T, Kim SP, Kim A, Killelea B, Gross C. Is there variation in private payor payments to cancer surgeons? A cross-sectional study in the USA. BMJ Open 2020, 10: e035438. PMID: 33020076, PMCID: PMC7537435, DOI: 10.1136/bmjopen-2019-035438.Peer-Reviewed Original ResearchBreast NeoplasmsCross-Sectional StudiesHumansMaleMastectomySurgeonsThoracic Surgery, Video-AssistedUnited States
2018
Factors Associated With Cancer Disparities Among Low-, Medium-, and High-Income US Counties
O’Connor J, Sedghi T, Dhodapkar M, Kane MJ, Gross CP. Factors Associated With Cancer Disparities Among Low-, Medium-, and High-Income US Counties. JAMA Network Open 2018, 1: e183146. PMID: 30646225, PMCID: PMC6324449, DOI: 10.1001/jamanetworkopen.2018.3146.Peer-Reviewed Original ResearchConceptsCancer death ratesDeath rateHigh-income countiesCancer disparitiesPossible mediatorsAge-standardized cancer death ratesLow-income countiesCross-sectional studyClinical care factorsIncome-related disparitiesNon-Hispanic blacksHealth risk behaviorsLow-quality careUS countiesPhysical inactivityCare factorsMAIN OUTCOMEFair healthDeath recordsMedian household incomeMedian incomeHealth StatisticsRisk behaviorsHealth policyCounty income levels
2006
The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening.
Gross CP, McAvay GJ, Krumholz HM, Paltiel AD, Bhasin D, Tinetti ME. The effect of age and chronic illness on life expectancy after a diagnosis of colorectal cancer: implications for screening. Annals Of Internal Medicine 2006, 145: 646-53. PMID: 17088577, DOI: 10.7326/0003-4819-145-9-200611070-00006.Peer-Reviewed Original ResearchConceptsChronic illnessColorectal cancerChronic conditionsLife expectancyCancer stageEarly-stage colorectal cancerPopulation-based cancer registriesPatients 67 yearsRetrospective cohort studyStage I cancerAdministrative claims dataChronic condition groupsFinal study sampleYears of ageShort life expectancyCohort studyEffect of agePatient ageI cancerCancer RegistryCancer variesHealthy patientsIndividual patientsMedicare claimsAdministrative claims
2004
Participation in Cancer Clinical Trials: Race-, Sex-, and Age-Based Disparities
Murthy VH, Krumholz HM, Gross CP. Participation in Cancer Clinical Trials: Race-, Sex-, and Age-Based Disparities. JAMA 2004, 291: 2720-2726. PMID: 15187053, DOI: 10.1001/jama.291.22.2720.Peer-Reviewed Original ResearchConceptsCancer trialsCancer clinical trialsClinical trialsTrial participantsEnrollment fractionWhite patientsAge groupsCross-sectional population-based analysisProstate cancer clinical trialsCancer research participationCancer trial participantsColorectal cancer trialsPatients 75 yearsIncident cancer patientsLung cancer trialsPopulation-based analysisRelative risk ratiosAge-based disparitiesYears of ageNational Cancer InstituteLogistic regression modelsLittle recent informationTrial enrolleesYounger patientsPatient group
1999
Management of Barrett's esophagus: a national study of practice patterns and their cost implications
Gross C, Canto M, Hixson J, Powe N. Management of Barrett's esophagus: a national study of practice patterns and their cost implications. The American Journal Of Gastroenterology 1999, 94: ajg1999806. PMID: 10606300, DOI: 10.1111/j.1572-0241.1999.01606.x.Peer-Reviewed Original ResearchConceptsHigh-grade dysplasiaDirect medical costsBarrett's esophagusEndoscopic surveillancePractice patternsMedical costsAge 45 yrNational cross-sectional surveyCurrent practice patternsLow-grade dysplasiaMajority of cliniciansFrequency of endoscopyDegree of dysplasiaPopulation-based estimatesCross-sectional surveySurveillance endoscopyNonclinical factorsBE patientsPhysician ageCost implicationsFrequent surveillanceDysplasiaGastroenterologistsClinical decisionOptimal managementThe Relation between Funding by the National Institutes of Health and the Burden of Disease
Gross C, Anderson G, Powe N. The Relation between Funding by the National Institutes of Health and the Burden of Disease. New England Journal Of Medicine 1999, 340: 1881-1887. PMID: 10369852, DOI: 10.1056/nejm199906173402406.Peer-Reviewed Original ResearchMeSH KeywordsBiomedical ResearchCost of IllnessCross-Sectional StudiesDiseaseFederal GovernmentHealth Care RationingHospitalizationHumansMorbidityMortalityNational Institutes of Health (U.S.)Quality-Adjusted Life YearsResearch Support as TopicResource AllocationSickness Impact ProfileSocial ChangeSocial ValuesUnited StatesConceptsBurden of diseaseYears of lifeHospital daysChronic obstructive pulmonary diseaseDisease-specific fundingObstructive pulmonary diseaseCross-sectional studyNational InstituteNIH fundingInstitute of MedicineNumber of deathsDiabetes mellitusPulmonary diseaseImmunodeficiency syndromePeptic ulcerPerinatal conditionsBreast cancerTotal mortalityDiseaseBurdenRegression analysisPrevalenceIncidenceHealthDays