2007
IGF‐1 stimulates de novo fatty acid biosynthesis by Schwann cells during myelination
Liang G, Cline GW, Macica CM. IGF‐1 stimulates de novo fatty acid biosynthesis by Schwann cells during myelination. Glia 2007, 55: 632-641. PMID: 17299765, DOI: 10.1002/glia.20496.Peer-Reviewed Original ResearchMeSH KeywordsAcetatesAnimalsCell CommunicationCells, CulturedCoculture TechniquesFatty AcidsGanglia, SpinalInsulin-Like Growth Factor IMembrane LipidsMyelin SheathNeurons, AfferentPeripheral Nervous SystemPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktRatsRats, Sprague-DawleySchwann CellsSignal TransductionConceptsInsulin-like growth factor-1Fatty acid synthesizing enzymesSynthesizing enzymesIGF-1 treatmentMyelin membrane formationGrowth factor-1PI3K/Akt pathwaySchwann cell differentiationPI3K/AktWestern blot analysisSciatic nerveIGF-1Schwann cellsElectrospray mass spectroscopy analysisCell coculturesMyelin-specific proteinsGrowth factorAkt pathwayMyelinationFactor 1Fatty acid synthesisCocultureBlot analysisEarly eventsMyelin membrane
1996
Arachidonic acid inhibits activity of cloned renal K+ channel, ROMK1
Macica CM, Yang Y, Hebert SC, Wang WH. Arachidonic acid inhibits activity of cloned renal K+ channel, ROMK1. American Journal Of Physiology 1996, 271: f588-f594. PMID: 8853420, DOI: 10.1152/ajprenal.1996.271.3.f588.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArachidonic AcidCaffeic AcidsCloning, MolecularCyclooxygenase InhibitorsCytochrome P-450 Enzyme InhibitorsFatty AcidsFatty Acids, UnsaturatedFemaleIndomethacinKidney MedullaKineticsLipoxygenase InhibitorsOocytesPatch-Clamp TechniquesPotassium Channel BlockersPotassium ChannelsRatsXenopus laevis