2012
Mineralizing Enthesopathy Is a Common Feature of Renal Phosphate-Wasting Disorders Attributed to FGF23 and Is Exacerbated by Standard Therapy in Hyp Mice
Karaplis A, Bai X, Falet J, Macica C. Mineralizing Enthesopathy Is a Common Feature of Renal Phosphate-Wasting Disorders Attributed to FGF23 and Is Exacerbated by Standard Therapy in Hyp Mice. Endocrinology 2012, 153: 5906-5917. PMID: 23038738, PMCID: PMC3512070, DOI: 10.1210/en.2012-1551.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsExtracellular Matrix ProteinsFamilial Hypophosphatemic RicketsFemaleFibroblast Growth Factor-23Fibroblast Growth FactorsGenetic Diseases, X-LinkedImmunohistochemistryKidneyMaleMiceMice, Inbred C57BLMice, TransgenicModels, GeneticMutationPedigreePhosphatesPhosphoproteinsRheumatic DiseasesTransgenesUp-RegulationConceptsPhosphate-wasting disordersStandard therapyFGF23 levelsElevated fibroblast growth factor 23Hyp miceRenal phosphate-wasting disordersFibroblast growth factor 23High FGF23 levelsGrowth factor 23Elevated FGF23 levelsAction of FGF23Dentin matrix acidic phosphoprotein 1Phosphate wasting disorderAutosomal recessive hypophosphatemic ricketsRecessive hypophosphatemic ricketsLigament insertion sitesChildhood managementOral phosphateFactor 23Achilles insertionDisease morbidityPotential morbidityBone spursUntoward effectsMurine model
2006
Induction of parathyroid hormone‐related peptide following peripheral nerve injury: Role as a modulator of Schwann cell phenotype
Macica CM, Liang G, Lankford KL, Broadus AE. Induction of parathyroid hormone‐related peptide following peripheral nerve injury: Role as a modulator of Schwann cell phenotype. Glia 2006, 53: 637-648. PMID: 16470617, DOI: 10.1002/glia.20319.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornCell DifferentiationCell ProliferationCells, CulturedCyclic AMP Response Element-Binding ProteinDisease Models, AnimalGanglia, SpinalGrowth ConesLigationMiceNerve RegenerationNeurons, AfferentParathyroid Hormone-Related ProteinPeripheral Nerve InjuriesPeripheral NervesRatsRats, Sprague-DawleyReceptor, Parathyroid Hormone, Type 1RNA, MessengerSchwann CellsSciatic NerveSciatic NeuropathyUp-RegulationConceptsSciatic nerve injury modelNerve injury modelPeripheral nerve injuryRole of PTHrPHormone-related peptideSchwann cellsSciatic nerveNerve injuryInjury modelNerve regenerationNervous systemParathyroid hormone-related peptideInjured sciatic nerveDedifferentiated Schwann cellsSchwann cell phenotypeRat nervous systemPeripheral nervous systemPTHrP receptor mRNASuccessful nerve regenerationType 1 collagen matrixSchwann cell culturesSympathetic gangliaPTHrP functionsPTHrP mRNAReceptor mRNA