Caroline Nelson, MD, FAAD
Assistant Professor of DermatologyCards
Appointments
Additional Titles
Director of Inpatient Dermatology, Dermatology
Director of Grand Rounds, Dermatology
About
Titles
Assistant Professor of Dermatology
Director of Inpatient Dermatology, Dermatology; Director of Grand Rounds, Dermatology
Biography
Caroline Nelson, MD is a medical dermatologist and Assistant Professor at the Yale School of Medicine. She is the Director of Inpatient Dermatology and Grand Rounds. She also sees outpatients at the Yale Medicine Dermatology New Haven and Branford clinics.
“As a medical student, what inspired me to go into dermatology was seeing the negative impact of skin diseases on quality of life. I wanted to make a difference, particularly for critically ill patients,” she says. Following her dermatology residency at the University of Pennsylvania, Dr. Nelson completed a fellowship in complex medical dermatology at the Brigham and Women’s Hospital and the Dana Farber Cancer Institute of Harvard Medical School.
At Yale, Dr. Nelson attends on the consult service and focuses her clinical and research activities on severe cutaneous adverse reactions, such as drug reaction with eosinophilia and systemic symptoms (DRESS) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). She also has expertise in neutrophilic skin disorders and paraneoplastic syndromes. In her outpatient clinics, Dr. Nelson performs skin cancer screenings and treats patients with a variety of skin problems, including acne, psoriasis, and eczema.
Dr. Nelson is passionate about medical education. She teaches the inpatient dermatology curriculum at Yale and has published a comprehensive board review and practice examinations to prepare residents for the American Board of Dermatology in-training and certification examinations. She finds particular fulfillment in her role as a longitudinal coach for Yale medical students. “Teaching is not simply about communicating facts,” she says, “it is about demonstrating how the doctor-patient relationship can improve the lives of patients with skin diseases.”
Appointments
Dermatology
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- Fellow
- Brigham and Women’s Hospital and the Dana Farber Cancer Institute, Harvard University (2019)
- Resident
- University of Pennsylvania (2018)
- Intern
- New York University (2015)
- MD
- Perelman School of Medicine at the University of Pennsylvania (2014)
- BA
- University of Chicago (2006)
Research
Overview
Medical Subject Headings (MeSH)
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Jason Kwah, MD, MSc
Jean Bolognia, MD
William Damsky, MD, PhD
Christine Ko, MD
Christopher Bunick, MD/PhD
Jeffrey Cohen, MD
Dermatology
Education, Medical
Publications
2023
Evaluation of potential instruments for quantifying necrobiosis lipoidica severity via physician evaluation and patient-reported outcomes
Hashemi D, Nelson C, Nyberg M, Das M, Rosenbach M. Evaluation of potential instruments for quantifying necrobiosis lipoidica severity via physician evaluation and patient-reported outcomes. Journal Of The American Academy Of Dermatology 2023, 89: 1305-1306. PMID: 37633461, DOI: 10.1016/j.jaad.2023.08.048.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsDrug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Part II diagnosis and management
Wei B, Fox L, Kaffenberger B, Korman A, Micheletti R, Mostaghimi A, Noe M, Rosenbach M, Shinkai K, Kwah J, Phillips E, Bolognia J, Damsky W, Nelson C. Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Part II diagnosis and management. Journal Of The American Academy Of Dermatology 2023, 90: 911-926. PMID: 37516356, DOI: 10.1016/j.jaad.2023.02.073.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSevere cutaneous adverse reactionsCutaneous adverse reactionsSystemic symptomsDrug reactionsAdverse reactionsDifferential diagnosisDrug-induced hypersensitivity syndrome/drug reactionDrug-induced hypersensitivity syndromeDiHS/DRESSVisceral organ involvementSteroid-sparing agentCornerstone of managementFirst-line therapyEvidence-based overviewSystemic corticosteroidsHypersensitivity syndromeImmediate discontinuationOrgan involvementRisk stratificationAutoimmune diseasesAdjunctive testNeoplastic disordersDiagnostic criteriaLongitudinal evaluationDiagnosisDrug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Part I. Epidemiology, pathogenesis, clinicopathological features, and prognosis
Wei B, Fox L, Kaffenberger B, Korman A, Micheletti R, Mostaghimi A, Noe M, Rosenbach M, Shinkai K, Kwah J, Phillips E, Bolognia J, Damsky W, Nelson C. Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms. Part I. Epidemiology, pathogenesis, clinicopathological features, and prognosis. Journal Of The American Academy Of Dermatology 2023, 90: 885-908. PMID: 37516359, DOI: 10.1016/j.jaad.2023.02.072.Peer-Reviewed Original ResearchCitationsAltmetricConceptsSevere cutaneous adverse reactionsDiHS/DRESSClinicopathological featuresSystemic symptomsDrug reactionsDrug-induced hypersensitivity syndrome/drug reactionDrug-induced hypersensitivity syndromePart I. EpidemiologyVisceral organ involvementCutaneous adverse reactionsRisk of relapseHypersensitivity syndromeOrgan involvementI. EpidemiologyOrgan dysfunctionSignificant morbidityAutoimmune diseasesAdverse reactionsDrug exposureT cellsCommon triggerImmune systemPathogenesisEosinophiliaMedical education activities1548 Identification of a neutrophil-specific PIK3R1 mutation facilitates targeted treatment in a patient with sweet syndrome
Bhattacharya S, Basu S, Sheng E, Wei J, Kersh A, Nelson C, Bryer J, Ashchyan H, Steele K, Forrestel A, Seykora J, Micheletti R, James W, Rosenbach M, Leung T. 1548 Identification of a neutrophil-specific PIK3R1 mutation facilitates targeted treatment in a patient with sweet syndrome. Journal Of Investigative Dermatology 2023, 143: s266. DOI: 10.1016/j.jid.2023.03.1566.Peer-Reviewed Original ResearchConceptsAssessing the Discriminatory Ability of Diagnostic Criteria for Ulcerative Pyoderma Gangrenosum and Its Mimickers
Ji-Xu A, Liakos W, Merleev A, Brüggen M, Nelson C. Assessing the Discriminatory Ability of Diagnostic Criteria for Ulcerative Pyoderma Gangrenosum and Its Mimickers. JAMA Dermatology 2023, 159: 337-338. PMID: 36652229, PMCID: PMC9857708, DOI: 10.1001/jamadermatol.2022.5978.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsIdentification of a neutrophil-specific PIK3R1 mutation facilitates targeted treatment in a patient with Sweet syndrome
Bhattacharya S, Basu S, Sheng E, Murphy C, Wei J, Kersh A, Nelson C, Bryer J, Ashchyan H, Steele K, Forrestel A, Seykora J, Micheletti R, James W, Rosenbach M, Leung T. Identification of a neutrophil-specific PIK3R1 mutation facilitates targeted treatment in a patient with Sweet syndrome. Journal Of Clinical Investigation 2023, 133: e162137. PMID: 36355435, PMCID: PMC9797331, DOI: 10.1172/jci162137.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsSteroid-sparing agentSweet's syndromeInflammatory diseasesCorticosteroid-related side effectsElevated IL-1Febrile neutrophilic dermatosisDramatic therapeutic responseReceptor 1 antagonistNeutrophil respiratory burstMultiorgan inflammatory diseasePersonalized medicine approachPI3K/AktSuccessful clinical interventionNeutrophilic dermatosisFrontline therapyRefractory casesNeutrophilic infiltrateBlood countIL-1βNeutrophil functionNeutrophil migrationTherapeutic responseLiver enzymesClinical challengeIL-1Caroline Nelson Dermatology: Comprehensive Board Review and Practice Examinations
Lippincott Williams & WilkinsBooks
2022
Reducing the carbon footprint of travel to an international dermatology conference: a case study of the Medical Dermatology Society's Carbon Footprint Program
Belzer A, Rosenbach M, Parker E, Barbieri J, Nelson C. Reducing the carbon footprint of travel to an international dermatology conference: a case study of the Medical Dermatology Society's Carbon Footprint Program. International Journal Of Dermatology 2022, 62: e377-e379. PMID: 36371718, DOI: 10.1111/ijd.16497.Peer-Reviewed Original ResearchCitationsLB1040 Treatment of sweet syndrome by molecular identification of PIK3R1 mutation
Bhattacharya S, Sheng E, Murphy C, Wei J, Kersh A, Nelson C, Bryer J, Ashchyan H, Steele K, Forrestel A, Seykora J, Micheletti R, James W, Rosenbach M, Leung T. LB1040 Treatment of sweet syndrome by molecular identification of PIK3R1 mutation. Journal Of Investigative Dermatology 2022, 142: b37. DOI: 10.1016/j.jid.2022.05.1078.Peer-Reviewed Original Research
2020
15995 Geographic disparities in access to scalp cooling for the prevention of chemotherapy-induced alopecia in the United States
Bui A, Singer S, Tkachenko E, Sharma P, Nelson C, LeBoeuf N, Mostaghimi A. 15995 Geographic disparities in access to scalp cooling for the prevention of chemotherapy-induced alopecia in the United States. Journal Of The American Academy Of Dermatology 2020, 83: ab166. DOI: 10.1016/j.jaad.2020.06.754.Peer-Reviewed Original Research
Academic Achievements and Community Involvement
activity Advances in DRESS Syndrome Research
Oral PresentationNational DRESS Syndrome DayDetails07/16/2023 - 07/16/2023https://www.youtube.com/watch?v=mNtBid37ceISponsored by DRESS Syndrome Foundationhonor Medical Education Fellowship
Yale School of Medicine AwardYale School of MedicineDetails06/01/2023United Stateshonor American Academy of Dermatology Presidential Citation
National AwardAmerican Academy of DermatologyDetails03/16/2023United Stateshonor Oscar Colegio Excellence in Dermatology Resident Teaching Award
Yale School of Medicine AwardYale Department of DermatologyDetails06/15/2022United Stateshonor American Academy of Dermatology Leadership Forum
National AwardAmerican Academy of DermatologyDetails04/29/2022United States
Links & Media
News
- June 20, 2023
18 Faculty Selected as Inaugural Longitudinal Coaches for MD Students
- June 15, 2023
Congratulations: MHS-Med Ed Pathway Graduates & Med Ed Fellows!
- March 26, 2022
Dermatology, telemedicine and the pandemic: can skin diagnosis be done from a distance?
- January 14, 2022
Autoimmune Disease and Skin Problems: Yale Researchers Uncover Clues to Improve Patient Care
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