2024
Sleep Deficiency and Pain in Persons With Substance Use Disorders
Buonora M, Sharma M, Falker C, Baldassarri S. Sleep Deficiency and Pain in Persons With Substance Use Disorders. Current Addiction Reports 2024, 11: 447-458. DOI: 10.1007/s40429-024-00562-2.Peer-Reviewed Original ResearchSubstance use disordersUse disorderSleep deficiencyPotential tissue damagePatterns of substance useShort sleep durationMaladaptive pattern of substance useTrajectories of substance useSubstance usePainNeurological changesComponents of sleepSleep timeSummaryThis reviewTissue damageClinical practiceHost factorsSleep durationLower sleep qualityDisordersSleepDeficiencyMaladaptive patternsSleep qualityEmotional experience
2023
Video-telecare collaborative pain management during COVID-19: a single-arm feasibility study
Rogers D, Frank J, Wesolowicz D, Nolan C, Schroeder A, Falker C, Abelleira A, Moore B, Becker W, Edmond S. Video-telecare collaborative pain management during COVID-19: a single-arm feasibility study. BMC Primary Care 2023, 24: 134. PMID: 37386370, PMCID: PMC10308713, DOI: 10.1186/s12875-023-02052-2.Peer-Reviewed Original ResearchConceptsMorphine equivalent daily doseSingle-arm feasibility studyEquivalent daily dosePain managementDaily doseLong-term opioid therapyInitial intakeMultiple appointmentsNon-pharmacologic interventionsOpioid use disorderPrimary care providersPain management programGuideline-based careEvidence-based interventionsBackgroundChronic painOpioid therapyBehavioral painChronic painPrimary careCommon conditionCare providersPatientsU.S. veteransPainPreliminary dataMedications for alcohol use disorder improve survival in patients with hazardous drinking and alcohol-associated cirrhosis
Rabiee A, Mahmud N, Falker C, Garcia-Tsao G, Taddei T, Kaplan D. Medications for alcohol use disorder improve survival in patients with hazardous drinking and alcohol-associated cirrhosis. Hepatology Communications 2023, 7: e0093. PMID: 36972386, PMCID: PMC10043587, DOI: 10.1097/hc9.0000000000000093.Peer-Reviewed Original ResearchConceptsAlcohol-associated cirrhosisAlcohol use disorderUse disordersCause mortalityImproved survivalPropensity scoreInpatient diagnosis codesRetrospective cohort studyCox regression analysisActive alcohol useCirrhosis decompensationCohort studyConcurrent diagnosisLiver diseasePotential confoundersDiagnosis codesVeteran outcomesCirrhosis diagnosisStrong negative predictorCirrhosisPatientsHazardous drinkingAlcohol use behaviorsCosts AssociatedAlcohol use
2022
Self-reported Use of Prescribed Buprenorphine Among US Adults With Nonmedical Use of Prescription Opioids Motivated by Pain
Buonora M, Sung M, Falker C, Black A, Becker W. Self-reported Use of Prescribed Buprenorphine Among US Adults With Nonmedical Use of Prescription Opioids Motivated by Pain. JAMA Network Open 2022, 5: e2241670. PMID: 36367731, PMCID: PMC9652749, DOI: 10.1001/jamanetworkopen.2022.41670.Peer-Reviewed Original ResearchWomen’s Use of Substance Use Disorder Treatment Services: Rates, Correlates, and Comparisons to Men
Falker CG, Stefanovics EA, Rhee TG, Rosenheck RA. Women’s Use of Substance Use Disorder Treatment Services: Rates, Correlates, and Comparisons to Men. Psychiatric Quarterly 2022, 93: 737-752. PMID: 35661318, DOI: 10.1007/s11126-022-09989-0.Peer-Reviewed Original ResearchConceptsSubstance use disordersSUD treatmentSubstance use disorder treatment servicesDSM-5 SUD diagnosesSUD treatment useReceipt of treatmentPast-year treatmentDisorder treatment servicesTreatment receiptSUD diagnosisTreatment useService useUse disordersGender differencesTreatment servicesWomenSignificant gender differencesMenSignificant differencesTreatmentSpite of evidenceWomen's useReceiptCorrelatesLittle informationPerioperative Buprenorphine Management A Multidisciplinary Approach
Hickey T, Abelleira A, Acampora G, Becker WC, Falker CG, Nazario M, Weimer MB. Perioperative Buprenorphine Management A Multidisciplinary Approach. Medical Clinics Of North America 2022, 106: 169-185. PMID: 34823729, DOI: 10.1016/j.mcna.2021.09.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAcetaminophenAgedAnalgesics, Non-NarcoticAnalgesics, OpioidAnti-Inflammatory Agents, Non-SteroidalArthroplasty, Replacement, HipBuprenorphineCombined Modality TherapyDrug CompoundingFemaleHumansInterdisciplinary CommunicationMaleOpiate Substitution TreatmentOpioid-Related DisordersPainPain ManagementPain, PostoperativePerioperative CareReceptors, Opioid, muConceptsOpioid use disorderBuprenorphine treatmentMu-opioid receptor availabilityAgonist opioid treatmentMultimodal analgesic strategyAnti-inflammatory drugsLong-term buprenorphine treatmentAnalgesic strategiesNonopioid adjunctsOpioid treatmentPerioperative strategiesHospital dischargePerioperative managementBuprenorphine formulationsSimultaneous administrationRegional anesthesiaEffective treatmentUse disordersReceptor availabilityMultidisciplinary approachBuprenorphinePatientsTreatmentPainAnesthesia
2021
Optimizing Interdisciplinary Virtual Pain Care and Buprenorphine Initiation During COVID-19: A Quality Improvement Study
Edmond SN, Currie S, Gehrke A, Falker CG, Sung M, Abelleira A, Edens EL, Becker WC. Optimizing Interdisciplinary Virtual Pain Care and Buprenorphine Initiation During COVID-19: A Quality Improvement Study. Pain Medicine 2021, 23: 1043-1046. PMID: 34940877, PMCID: PMC9383145, DOI: 10.1093/pm/pnab348.Peer-Reviewed Original ResearchTraining Medical Students, Residents, and Fellows in Opioid Use Disorder Treatment
Morford K, Falker C, Tetrault J. Training Medical Students, Residents, and Fellows in Opioid Use Disorder Treatment. 2021, 161-171. DOI: 10.1007/978-3-030-80818-1_11.Peer-Reviewed Original ResearchMedical educationCompetency-based assessmentOpioid use disorderEducational gapMedical studentsRole modelingTrainee assessmentEffective workforceCore contentEarly clinical experienceEducational interventionTraining materialsTraining levelEducationSpecific instructionsFirst-line treatment optionOpioid use disorder treatmentKey recommendationsLarge treatment gapClinical experienceOpioid-related morbidityEvidence-based treatmentsUse disorder treatmentCurriculumInstitutional strengthThe Need for Multidisciplinary Hospital Teams for Injection Drug Use-related Infective Endocarditis
Weimer MB, Falker CG, Seval N, Golden M, Hull SC, Geirsson A, Vallabhajosyula P. The Need for Multidisciplinary Hospital Teams for Injection Drug Use-related Infective Endocarditis. Journal Of Addiction Medicine 2021, 16: 375-378. PMID: 34510088, DOI: 10.1097/adm.0000000000000916.Commentaries, Editorials and LettersConceptsInjection drug use-related infective endocarditisCardiac surgeryInfective endocarditisAddiction treatmentInjection drug useCare of patientsMultidisciplinary hospital teamSubstance use disordersMost patientsUse disordersPatientsDrug useSurgical needsHospital teamIDUsCase managementInfectious diseasesAddiction medicineMultidisciplinary approachEndocarditisSurgeryTreatmentDiseaseComplex diseasesAnesthesiaAn Interdisciplinary Approach to Metastatic Pancreatic Cancer and Comorbid Opioid Use Disorder Treatment Within a VA Health Care System.
Ruskin A, Falker CG, Edens EL, Bauer MR. An Interdisciplinary Approach to Metastatic Pancreatic Cancer and Comorbid Opioid Use Disorder Treatment Within a VA Health Care System. Federal Practitioner 2021, 38: s66-s71. PMID: 34733097, PMCID: PMC8560123, DOI: 10.12788/fp.0160.Peer-Reviewed Original ResearchPancreatic cancerOpioid use disorder treatmentVA health care systemActive substance use disorderAdvanced pancreatic cancerMetastatic pancreatic cancerUse disorder treatmentSubstance use disordersHealth care systemUse disordersDisorder treatmentCancer treatmentCare systemMultidisciplinary approachCancerTreatmentPatientsSleep Disturbance Is Associated With the Presence of Portosystemic Collaterals in Patients With Compensated Cirrhosis
Balakrishnan M, Falker C, Conley S, Ciarleglio M, Deng Y, Redeker NS, Garcia‐Tsao G. Sleep Disturbance Is Associated With the Presence of Portosystemic Collaterals in Patients With Compensated Cirrhosis. Hepatology Communications 2021, 5: 491-501. PMID: 33681681, PMCID: PMC7917284, DOI: 10.1002/hep4.1636.Peer-Reviewed Original ResearchConceptsPortosystemic collateralsSleep disturbancesCompensated cirrhosisSleep fragmentationSleep characteristicsHigher international normalized ratioPittsburgh Sleep Quality IndexLower total sleep timeMultivariable linear regression analysisSignificant portal hypertensionGroup of patientsInternational normalized ratioEpworth Sleepiness ScaleSleep Quality IndexGreater sleep fragmentationCross-sectional studyMore sleep disturbancesMore sleep fragmentationTotal sleep timeLower sleep efficiencyPresence of collateralsCollateral presencePortal hypertensionLow albuminExcessive daytime
2009
Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2–dependent fibrinolysis
Jacovina AT, Deora AB, Ling Q, Broekman MJ, Almeida D, Greenberg CB, Marcus AJ, Smith JD, Hajjar KA. Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2–dependent fibrinolysis. Journal Of Clinical Investigation 2009, 119: 3384-3394. PMID: 19841537, PMCID: PMC2769184, DOI: 10.1172/jci39591.Peer-Reviewed Original Research