2024
Exploring Dietary Restraint as a Mediator of Behavioral and Cognitive‐Behavioral Treatments on Outcomes for Patients With Binge‐Eating Disorder With Obesity
Grilo C, Pittman B. Exploring Dietary Restraint as a Mediator of Behavioral and Cognitive‐Behavioral Treatments on Outcomes for Patients With Binge‐Eating Disorder With Obesity. International Journal Of Eating Disorders 2024 PMID: 39247962, DOI: 10.1002/eat.24288.Peer-Reviewed Original ResearchCognitive-behavioral therapyBehavioral weight lossBinge-eating disorderBinge eatingWeight loss outcomesCognitive-behavioral treatmentMediation of behaviorEDE-Q restraintPost-treatmentCognitive-behavioralRestraint ScaleDietary restraintBingeMediation effectEatingEffects of treatmentTreatment effectsDisordersRandomized controlled trialsWeight lossMonths of treatmentHypothesis-testingSecondary analysisRestraintBinge-eating
2023
Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial
Grilo C, Lydecker J, Jastreboff A, Pittman B, McKee S. Naltrexone/bupropion for binge‐eating disorder: A randomized, double‐blind, placebo‐controlled trial. Obesity 2023, 31: 2762-2773. PMID: 37751990, PMCID: PMC10600891, DOI: 10.1002/oby.23898.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderObesity statusLogistic regressionWeight lossPlacebo-controlled trialWeight loss outcomesPrevalent psychiatric disordersEvidence-based treatmentsPost-treatment assessmentBinge-eating frequencyGreater percentage weight lossMedication outcomesRemission ratePharmacological optionsPlaceboBupropionPsychiatric disordersPercentage weight lossMixed modelsDisordersObesityPatientsSignificant reductionWeight reductionPsychiatric comorbidity as a prospective predictor of long-term weight and psychosocial outcomes after bariatric surgery
Ivezaj V, Dilip A, Grilo C. Psychiatric comorbidity as a prospective predictor of long-term weight and psychosocial outcomes after bariatric surgery. General Hospital Psychiatry 2023, 83: 51-58. PMID: 37099869, DOI: 10.1016/j.genhosppsych.2023.03.005.Peer-Reviewed Original ResearchConceptsEating Disorder Examination-Bariatric Surgery VersionLong-term weight outcomesPost-bariatric surgeryPsychiatric comorbidityEating-disorder psychopathologyBariatric surgeryWeight outcomesMonths post-bariatric surgeryMini International Neuropsychiatric InterviewWeight loss outcomesCurrent psychiatric disorderCurrent psychiatric comorbidityInternational Neuropsychiatric InterviewPsychosocial functioning outcomesLong-term weightBeck Depression InventoryPoor psychosocial functioningPrognostic significanceProspective studyBariatric populationNeuropsychiatric InterviewClinical significanceComorbiditiesLoss outcomesPsychiatric disordersPredictors and significance of rapid response to behaviorally based treatment of binge eating disorder
Yurkow S, Ivezaj V, Grilo C. Predictors and significance of rapid response to behaviorally based treatment of binge eating disorder. Obesity 2023, 31: 390-398. PMID: 36623872, PMCID: PMC9877118, DOI: 10.1002/oby.23648.Peer-Reviewed Original ResearchConceptsDemographic featuresTreatment attitudesWeight lossFourth treatment weekWeight loss outcomesPsychiatric variablesSuperior clinical outcomesWeight loss treatmentTreatment of bingeClinical severity variablesClinical outcomesPrognostic significanceTreatment weekClinical trialsBaseline predictorsLoss outcomesLoss treatmentPosttreatment outcomesBinge eatingIndependent assessorsBingeSeverity variablesDisordersPatientsTreatment
2016
Loss-of-control eating following sleeve gastrectomy surgery
Ivezaj V, Kessler EE, Lydecker JA, Barnes RD, White MA, Grilo CM. Loss-of-control eating following sleeve gastrectomy surgery. Surgery For Obesity And Related Diseases 2016, 13: 392-398. PMID: 27913121, PMCID: PMC5357454, DOI: 10.1016/j.soard.2016.09.028.Peer-Reviewed Original ResearchConceptsSleeve gastrectomy surgeryGastrectomy surgeryWeight lossEating Disorder Examination-Bariatric Surgery VersionPoorer weight loss outcomesBED criteriaLower percent weight lossPoor weight lossWeight loss outcomesBody mass indexEating-disorder psychopathologyBinge-eating disorderRegular compensatory behaviorsCurrent mean ageUnited States METHODSBariatric surgeryPostoperative lossMass indexPercent weight lossMean ageMonths postsurgeryPoor outcomeLoss outcomesGreater severitySurgery
2015
Prognostic Significance of Depressive Symptoms on Weight Loss and Psychosocial Outcomes Following Gastric Bypass Surgery: A Prospective 24-Month Follow-Up Study
White MA, Kalarchian MA, Levine MD, Masheb RM, Marcus MD, Grilo CM. Prognostic Significance of Depressive Symptoms on Weight Loss and Psychosocial Outcomes Following Gastric Bypass Surgery: A Prospective 24-Month Follow-Up Study. Obesity Surgery 2015, 25: 1909-1916. PMID: 25720515, PMCID: PMC4551611, DOI: 10.1007/s11695-015-1631-9.Peer-Reviewed Original ResearchConceptsGastric bypass surgeryPostoperative depressive symptomsElevated depressive symptomsDepressive symptomsBypass surgeryWeight outcomesPrognostic significanceDisorder psychopathologyLong-term weight outcomesWeight lossPoorer weight outcomesPreoperative depressive symptomsBariatric surgery patientsWeight loss outcomesSignificant depressive symptomsMethodsThree hundred fiftyQuality of lifeBeck Depression InventorySurgery patientsBattery of assessmentsHundred fiftyLoss outcomesBackgroundThis studySurgeryClinical attention
2014
A randomized controlled trial comparing scalable weight loss treatments in primary care
Barnes RD, White MA, Martino S, Grilo CM. A randomized controlled trial comparing scalable weight loss treatments in primary care. Obesity 2014, 22: 2508-2516. PMID: 25298016, PMCID: PMC4236282, DOI: 10.1002/oby.20889.Peer-Reviewed Original ResearchConceptsNutrition psychoeducationUsual careAttention control interventionMotivational interviewingTreatment adherenceWeight lossOverweight/obese patientsBed statusWeight loss outcomesPrimary care settingWeight loss treatmentWeight loss resultsObese patientsTriglyceride levelsPrimary careObesity interventionsNPC patientsLoss outcomesLoss treatmentDepression scoresScalable interventionsPatientsTreatment disseminationSuperior benefitsIntervention
2009
Loss of control over eating predicts outcomes in bariatric surgery patients: a prospective, 24-month follow-up study.
White MA, Kalarchian MA, Masheb RM, Marcus MD, Grilo CM. Loss of control over eating predicts outcomes in bariatric surgery patients: a prospective, 24-month follow-up study. The Journal Of Clinical Psychiatry 2009, 71: 175-84. PMID: 19852902, PMCID: PMC2831110, DOI: 10.4088/jcp.08m04328blu.Peer-Reviewed Original ResearchConceptsBariatric surgery patientsSurgery patientsQuality of lifeGastric bypass surgery patientsDisorder psychopathologyWeight lossPostsurgical weight lossBypass surgery patientsWeight loss outcomesNegative prognostic indicatorBariatric surgeryPostoperative outcomesPostsurgical outcomesPrognostic indicatorBattery of assessmentsClinical significancePostsurgical improvementLoss outcomesMixed model analysisClinical attentionPatientsSurgeryPostsurgeryDepression levelsPsychosocial outcomes
2005
Eating patterns and breakfast consumption in obese patients with binge eating disorder
Masheb RM, Grilo CM. Eating patterns and breakfast consumption in obese patients with binge eating disorder. Behaviour Research And Therapy 2005, 44: 1545-1553. PMID: 16376851, DOI: 10.1016/j.brat.2005.10.013.Peer-Reviewed Original ResearchConceptsBreakfast consumptionWeight loss outcomesTreatment of BEDFrequency of mealsHalf of participantsObese patientsObese individualsImportant clinical applicationsLoss outcomesFrequent mealsSpecific interventionsBingeBreakfastClinical applicationDisorder featuresMealSelf-report measuresDaysDisordersTreatmentParticipantsSnacksSemi-structured interviewsPatients