2023
Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial
Grilo C, Lydecker J, Gueorguieva R. Cognitive‐behavioral therapy for binge‐eating disorder for non‐responders to initial acute treatments: Randomized controlled trial. International Journal Of Eating Disorders 2023, 56: 1544-1553. PMID: 37144325, PMCID: PMC10524840, DOI: 10.1002/eat.23975.Peer-Reviewed Original ResearchConceptsInitial acute treatmentBinge-eating disorderCognitive behavioral therapyAcute treatmentBinge-eating frequencyInitial interventionTherapist-led cognitive behavioural therapyInitial pharmacological treatmentTreat remission ratesEvidence-based treatmentsSingle-site trialAcute efficacyRemission rateAdult patientsInitial treatmentPharmacological treatmentPatientsPosttreatment assessmentBehavioral treatmentSufficient benefitTherapyDisordersInterventionTreatmentPharmacotherapy
2005
Cognitive Behavioral Therapy Guided Self-Help and Orlistat for the Treatment of Binge Eating Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial
Grilo CM, Masheb RM, Salant SL. Cognitive Behavioral Therapy Guided Self-Help and Orlistat for the Treatment of Binge Eating Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial. Biological Psychiatry 2005, 57: 1193-1201. PMID: 15866560, DOI: 10.1016/j.biopsych.2005.03.001.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyWeight lossSelf-help cognitive behavioral therapyAddition of placeboFacilitate weight lossTreat remission ratesPercent of patientsDouble-blind fashionPlacebo-controlled studyAddition of orlistatGreater weight lossGuided Self-HelpObese BED patientsBinge Eating DisorderRemission rateTreatment discontinuationClinical improvementObesity medicationsBED patientsCBTgshOrlistatPlaceboBehavioral therapyDisorder psychopathologyComparable improvementEfficacy of cognitive behavioral therapy and fluoxetine for the treatment of binge eating disorder: A randomized double-blind placebo-controlled comparison
Grilo CM, Masheb RM, Wilson GT. Efficacy of cognitive behavioral therapy and fluoxetine for the treatment of binge eating disorder: A randomized double-blind placebo-controlled comparison. Biological Psychiatry 2005, 57: 301-309. PMID: 15691532, DOI: 10.1016/j.biopsych.2004.11.002.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyBehavioral therapyEfficacy of CBTTreatment of bingeTreat remission ratesCBT conditionCognitive featuresPsychological featuresPsychological distressDimensional measuresBingeRemission rateDouble-blind placebo-controlled comparisonDouble-blind fashionPlacebo-controlled comparisonPlacebo-controlled studyConsistent findingCompletersIndividual treatmentCertain medicationsPharmacological therapyITT analysisFluoxetineDisordersPlacebo