2023
Naltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial
Grilo C, Lydecker J, Gueorguieva R. Naltrexone plus bupropion combination medication maintenance treatment for binge-eating disorder following successful acute treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2023, 53: 7775-7784. PMID: 37366017, PMCID: PMC10751383, DOI: 10.1017/s0033291723001800.Peer-Reviewed Original ResearchConceptsNaltrexone/bupropionBinge-eating disorderBinge-eating remissionAcute treatmentMaintenance treatmentBinge-eating frequencyDouble-blind placebo-controlled trialBehavioral weight loss therapyWeight lossCo-occurring obesitySuccessful acute treatmentPlacebo-controlled trialWeight loss therapySignificant additional weight lossSingle-site trialAdditional weight lossAcute efficacyRemission rateAdult patientsComorbid obesityBupropionInitial interventionPosttreatment assessmentRespondersPlacebo
2017
Rumination in Patients with Binge‐Eating Disorder and Obesity: Associations with Eating‐Disorder Psychopathology and Weight‐bias Internalization
Wang SB, Lydecker JA, Grilo CM. Rumination in Patients with Binge‐Eating Disorder and Obesity: Associations with Eating‐Disorder Psychopathology and Weight‐bias Internalization. European Eating Disorders Review 2017, 25: 98-103. PMID: 28078784, PMCID: PMC5318238, DOI: 10.1002/erv.2499.Peer-Reviewed Original ResearchConceptsShape/weightWeight bias internalizationEating-disorder psychopathologyBinge-eating disorderCognitive processesGreater eating-disorder psychopathologyImportant cognitive processesOvervaluation of shapeGreater weight bias internalizationHierarchical multiple regressionTreatment-seeking patientsGreater ruminationRuminationDiscrimination experiencesPhysical healthPsychopathologyNegative attitudesMultiple regressionOvervaluationObesity treatmentComorbid obesityAttitudesDisordersExperienceFindings
2016
Sex Differences and Correlates of Pain in Patients with Comorbid Obesity and Binge Eating Disorder
Masheb RM, White MA, Grilo CM. Sex Differences and Correlates of Pain in Patients with Comorbid Obesity and Binge Eating Disorder. European Eating Disorders Review 2016, 24: 247-250. PMID: 26841114, PMCID: PMC4821688, DOI: 10.1002/erv.2432.Peer-Reviewed Original ResearchConceptsCorrelates of painMetabolic risk factorsRisk factorsHigh-density lipoprotein cholesterolObesity-related health risksBrief Pain InventoryPresence of painGreater pain severitySample of patientsSex differencesTreatment-seeking patientsComorbid obesityLipoprotein cholesterolPain severityPain InventoryComorbid painPain interferenceMore painPainMetabolic markersBinge frequencyAnalysis of covarianceComorbid bingeClinical implicationsPatients