2017
The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease
Cazanave S, Podtelezhnikov A, Jensen K, Seneshaw M, Kumar DP, Min HK, Santhekadur PK, Banini B, Mauro AG, M. Oseini A, Vincent R, Tanis KQ, Webber AL, Wang L, Bedossa P, Mirshahi F, Sanyal AJ. The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease. Scientific Reports 2017, 7: 17193. PMID: 29222421, PMCID: PMC5722878, DOI: 10.1038/s41598-017-17370-6.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDisease ProgressionGene Expression ProfilingLiver CirrhosisMaleMiceMice, Inbred C57BLNon-alcoholic Fatty Liver DiseaseSignal TransductionConceptsNonalcoholic fatty liver diseaseFatty liver diseaseAdvanced fibrosisLiver diseaseMacrophage activationPathway activationHepatic stellate cell activationFatty liver developmentStellate cell activationOxidative stress pathwaysCell deathAdvanced diseaseMetabolic pathway activationChow dietFatty liverEarly fibrosisFibrogenic pathwaysCell stressSuch miceAnimal modelsCell activationFibrosisMetabolic perturbationsDiseaseOxidative stress
2006
Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators
Keller MA, Addya S, Vadigepalli R, Banini B, Delgrosso K, Huang H, Surrey S. Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators. Physiological Genomics 2006, 28: 114-128. PMID: 16940433, DOI: 10.1152/physiolgenomics.00055.2006.Peer-Reviewed Original ResearchConceptsTranscriptional regulatory network analysisRegulatory network analysisTranscriptional regulatorsErythroid differentiation systemProbe setsCluster of genesPotential transcriptional regulatorsBlood cell lineagesDifferent expression patternsHuman erythroid progenitorsMRNA expression profilingBlood cell transcriptomeNetwork analysisErythroid developmentHematopoietic stem cellsCell transcriptomeDE genesTranscription factorsHematopoietic progenitor cellsEvi-1Target genesMolecular basisExpression profilingHuman erythropoiesisCell lineages