2006
Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators
Keller MA, Addya S, Vadigepalli R, Banini B, Delgrosso K, Huang H, Surrey S. Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators. Physiological Genomics 2006, 28: 114-128. PMID: 16940433, DOI: 10.1152/physiolgenomics.00055.2006.Peer-Reviewed Original ResearchConceptsTranscriptional regulatory network analysisRegulatory network analysisTranscriptional regulatorsErythroid differentiation systemProbe setsCluster of genesPotential transcriptional regulatorsBlood cell lineagesDifferent expression patternsHuman erythroid progenitorsMRNA expression profilingBlood cell transcriptomeNetwork analysisErythroid developmentHematopoietic stem cellsCell transcriptomeDE genesTranscription factorsHematopoietic progenitor cellsEvi-1Target genesMolecular basisExpression profilingHuman erythropoiesisCell lineages
2005
Transcriptome Analysis of Human Hematopoietic Progenitor Cells during In Vitro Erythroid Differentiation.
Keller M, Addya S, Vadigepalli R, Ponte C, Banini B, Delgrosso K, Surrey S. Transcriptome Analysis of Human Hematopoietic Progenitor Cells during In Vitro Erythroid Differentiation. Blood 2005, 106: 1750. DOI: 10.1182/blood.v106.11.1750.1750.Peer-Reviewed Original ResearchTranscriptional regulatory elementsHematopoietic progenitor cellsHuman hematopoietic progenitor cellsDE genesTranscriptional regulatory network analysisTranscription factor occupancyGlobin gene expressionTranscriptional regulatory networksErythroid-specific genesTranscription factor interactionsAffymetrix Human Genome U133Different gene clustersRegulatory network analysisHuman erythroid cellsProgenitor cellsHuman Genome U133Presence of EpoMultiple cell typesFactor occupancyΓ-globin mRNAGene clusterGATA-1Transcriptome analysisHematopoietic stem cellsRegulatory networks