1989
A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation.
Bierer B, Burakoff S, Smith B. A large proportion of T lymphocytes lack CD5 expression after bone marrow transplantation. Blood 1989, 73: 1359-66. PMID: 2467708, DOI: 10.1182/blood.v73.5.1359.bloodjournal7351359.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAntigens, DifferentiationAntigens, Differentiation, T-LymphocyteBone Marrow TransplantationCalciumCD3 ComplexCD5 AntigensCytoplasmCytotoxicity, ImmunologicGraft vs Host DiseaseHumansImmunologic Deficiency SyndromesInterleukin-2Leukocyte CountMicePhenotypeReceptors, Antigen, T-CellT-Lymphocytes, CytotoxicConceptsBone marrow transplantationCD5 expressionMarrow transplantationT cellsAllogeneic bone marrow transplantationFrequency of CD3Major histocompatibility complex compatibilityT-cell depletionPercent of CD8Expression of CD5Presence of graftBMT patientsTotal CD3Host diseaseInterstitial pneumonitisPreparative regimenPeripheral bloodT lymphocytesB cellsCD3Lectin stimulationPatientsNormal populationTransplantationCD5
1988
REGULATION OF CYTOTOXIC T LYMPHOCYTE-MEDIATED GRAFT REJECTION FOLLOWING BONE MARROW
Bierer B, Emerson S, Antin J, Maziarz R, Rappeport J, Smith B, Burakoff A. REGULATION OF CYTOTOXIC T LYMPHOCYTE-MEDIATED GRAFT REJECTION FOLLOWING BONE MARROW. Transplantation 1988, 46: 835-839. PMID: 3061078, DOI: 10.1097/00007890-198812000-00009.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAntibodies, MonoclonalAntigens, Differentiation, T-LymphocyteBone Marrow TransplantationCells, CulturedCytotoxicity, ImmunologicGraft RejectionHumansMaleT-Lymphocytes, CytotoxicConceptsGraft rejectionHuman allogeneic bone marrow transplantationT cell-depleted marrowAllogeneic bone marrow transplantationClass I major histocompatibility complex antigensMajor histocompatibility complex antigensLymphocyte function-associated antigen-1Bone marrow transplantationFunction-associated antigen-1Cytotoxic T lymphocytesAnti-CD3 mAbHistocompatibility complex antigensBone marrow progenitor cellsMHC class IMarrow progenitor cellsNumber of mAbsBMT patientsCTL activityEffector cellsMarrow transplantationRecipient originT cellsT lymphocytesComplex antigensBone marrow
1986
FUNCTIONAL ASSESSMENT OF T CELL DEPLETION FROM BONE MARROW PRIOR TO THERAPEUTIC TRANSPLANTATION USING LIMITING DILUTION CULTURE METHODS
Rozans M, Smith B, Emerson S, Crimmins M, Laurent G, Reichert T, Burakoff S, Miller R. FUNCTIONAL ASSESSMENT OF T CELL DEPLETION FROM BONE MARROW PRIOR TO THERAPEUTIC TRANSPLANTATION USING LIMITING DILUTION CULTURE METHODS. Transplantation 1986, 42: 380-386. PMID: 3094209, DOI: 10.1097/00007890-198610000-00010.Peer-Reviewed Original ResearchConceptsT-cell depletionT cellsComplement-mediated depletionCell depletionFACS analysisIL-2Functional impairmentT-lymphocyte depletionT-cell contaminationBone marrow inoculumT cell setsComplement-mediated lysisDilution methodFlow cytometric methodLymphocyte depletionComplement treatmentMarrow inoculumCytotoxic effectorsInterleukin-2Functional assessmentT101 immunotoxinCulture methodCytometric methodCell contaminationEventual death
1985
Phenotype of recovering lymphoid cell populations after marrow transplantation.
Ault KA, Antin JH, Ginsburg D, Orkin SH, Rappeport JM, Keohan ML, Martin P, Smith BR. Phenotype of recovering lymphoid cell populations after marrow transplantation. Journal Of Experimental Medicine 1985, 161: 1483-1502. PMID: 3159819, PMCID: PMC2187630, DOI: 10.1084/jem.161.6.1483.Peer-Reviewed Original Research