2003
Neutrophil CD11b upregulation during cardiopulmonary bypass is associated with postoperative renal injury
Rinder CS, Fontes M, Mathew JP, Rinder HM, Smith BR, Group M. Neutrophil CD11b upregulation during cardiopulmonary bypass is associated with postoperative renal injury. The Annals Of Thoracic Surgery 2003, 75: 899-905. PMID: 12645714, DOI: 10.1016/s0003-4975(02)04490-9.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdultAgedCardiopulmonary BypassCD11b AntigenCoronary Artery BypassCreatinineHeart FailureHeart Valve Prosthesis ImplantationHemodynamicsHumansIntra-Aortic Balloon PumpingLeukocyte CountMiddle AgedNeutrophilsPostoperative ComplicationsProspective StudiesRisk FactorsSystemic Inflammatory Response SyndromeConceptsAcute renal injuryNeutrophil CD11b upregulationRenal injuryCardiopulmonary bypassInflammatory responseCD11b upregulationAdult respiratory distress syndromeMarkers of leukocytesPlatelet CD62P expressionPostoperative hemodynamic supportPostoperative renal injuryNeutrophil inflammatory responseSystemic inflammatory responseRespiratory distress syndromeSubset of patientsC-reactive proteinTotal neutrophil countMonocyte CD11bRenal riskHemodynamic instabilityInflammatory markersPost-CPBHemodynamic supportMyeloperoxidase levelsNeutrophil count
2001
Platelet PlA2 polymorphism enhances risk of neurocognitive decline after cardiopulmonary bypass
Mathew J, Rinder C, Howe J, Fontes M, Crouch J, Newman M, Phillips-Bute B, Smith B, Group T. Platelet PlA2 polymorphism enhances risk of neurocognitive decline after cardiopulmonary bypass. The Annals Of Thoracic Surgery 2001, 71: 663-666. PMID: 11235724, DOI: 10.1016/s0003-4975(00)02335-3.Peer-Reviewed Original ResearchConceptsMini-Mental State ExaminationPlA1/A1PlA1/A2Cardiopulmonary bypassNeurocognitive declinePlA2 polymorphismPlatelet GPIIIaState ExaminationBaseline Mini-Mental State ExaminationGreater neurocognitive declineProthrombotic genetic factorsPostoperative day 4Prothrombotic risk factorsEmbolic insultFrequent complicationPlA2 allelePlaque embolizationLocal thrombosisRisk factorsThrombotic processCardiovascular settingsPlA2 genotypeNeurocognitive changesDay 4Multivariate analysis
1998
Correlation of Thrombosis With Increased Platelet Turnover in Thrombocytosis
Rinder H, Schuster J, Rinder C, Wang C, Schweidler H, Smith B. Correlation of Thrombosis With Increased Platelet Turnover in Thrombocytosis. Blood 1998, 91: 1288-1294. PMID: 9454759, DOI: 10.1182/blood.v91.4.1288.Peer-Reviewed Original ResearchConceptsRP countsNormal platelet countPlatelet countThrombocytosis patientsPlatelet turnoverHealthy controlsART patientsTreatment responsePrimary myeloproliferative disordersElevated platelet countSymptoms of thrombosisAspirin therapyRecurrent thrombosisThrombotic complicationsAspirin treatmentArterial thrombosisDVT patientsThrombotic riskTransient thrombocytosisThrombosis riskDeep veinsSecondary thrombocytosisAbsolute countsMyeloproliferative disordersThrombosis
1990
Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease.
Antin JH, Bierer BE, Smith BR, Guinan EC, Provost MM, Ferrara J, Macklis RM, Tarbell NJ, Blythman H, Bouloux C. Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease. Progress In Clinical And Biological Research 1990, 333: 207-15. PMID: 1689852.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntibodies, MonoclonalAntigens, CDAntigens, DifferentiationBone MarrowBone Marrow CellsBone Marrow TransplantationCD5 AntigensChildChild, PreschoolCombined Modality TherapyCyclophosphamideCytarabineDrug EvaluationGraft vs Host DiseaseHumansImmunotoxinsLeukemiaMiddle AgedMyelodysplastic SyndromesRicinRisk FactorsT-LymphocytesWhole-Body Irradiation