2018
Results of Phase 1 study on cytoreductive radical prostatectomy in men with newly diagnosed metastatic prostate cancer
Yuh B, Kwon Y, Shinder B, Singer E, Jang T, Kim S, Stein M, Mayer T, Ferrari A, Lee N, Parikh R, Ruel N, Kim W, Horie S, Byun S, Ahlering T, Kim I. Results of Phase 1 study on cytoreductive radical prostatectomy in men with newly diagnosed metastatic prostate cancer. Prostate International 2018, 7: 102-107. PMID: 31485434, PMCID: PMC6713798, DOI: 10.1016/j.prnil.2018.10.002.Peer-Reviewed Original ResearchMetastatic prostate cancerCytoreductive radical prostatectomyPhase 1 studyProstate-specific antigenRadical prostatectomyCytoreductive surgeryProstate cancerSpecific antigenDeath 5 monthsAcute tubular necrosisMajor perioperative complicationsOverall complication rateRapid disease progressionDay of surgerySubset of menPerioperative complicationsPrimary endpointTemporary dialysisComplication rateDisseminated diseaseTubular necrosisMajor complicationsMean ageClinical trialsDisease progression
2017
Risk of complications and urinary incontinence following cytoreductive prostatectomy: a multi-institutional study
Kim DK, Parihar JS, Kwon YS, Kim S, Shinder B, Lee N, Farber N, Ahlering T, Skarecky D, Yuh B, Ruel N, Kim WJ, Rha KH, Kim IY. Risk of complications and urinary incontinence following cytoreductive prostatectomy: a multi-institutional study. Asian Journal Of Andrology 2017, 20: 9-14. PMID: 28440262, PMCID: PMC5753561, DOI: 10.4103/1008-682x.196852.Peer-Reviewed Original ResearchConceptsMetastatic prostate cancerCytoreductive prostatectomyUrinary incontinenceProstate cancerBlood lossRadical prostatectomyCare androgen-deprivation therapyBenefit of cytoreductionUrinary incontinence rateAndrogen deprivation therapyMulti-institutional clinical trialsIncidence of complicationsMajor complication rateOnly independent predictorLonger operative timeRisk of complicationsTertiary surgical centerMulti-institutional studyDeprivation therapyBony metastasesIncontinence ratesPerioperative complicationsComplication rateCRP groupIndependent predictors