2020
The human microbiome and genitourinary malignancies
Nicolaro M, Portal D, Shinder B, Patel H, Singer E. The human microbiome and genitourinary malignancies. Annals Of Translational Medicine 2020, 8: 1245. PMID: 33178777, PMCID: PMC7607065, DOI: 10.21037/atm-20-2976.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsImmune checkpoint inhibitorsTyrosine kinase inhibitorsGenitourinary malignanciesResponse to certain drugsCheckpoint inhibitorsPredictors of diseaseOncological outcomesEffects of antibioticsProstate cancerMicrobial signaturesUrological malignanciesEtiology of disease statesTreatment coursePrognostic indicatorBladder cancerSystemic inflammationHealthy patientsUrinary microbiomeKidney cancerKinase inhibitorsMalignancyGenitourinary diseasesHuman microbiomeTherapeutic targetCancer
2018
Role of the androgen signaling axis in genitourinary malignancies.
Shinder B, Shupe A, Lee G, Stein M, Kim I, Singer E. Role of the androgen signaling axis in genitourinary malignancies. Translational Cancer Research 2018, 7: 1135-1142. PMID: 30701159, PMCID: PMC6349041, DOI: 10.21037/tcr.2018.03.41.Peer-Reviewed Original ResearchRenal cell carcinomaGenitourinary malignanciesAndrogen receptorBladder cancerRole of ARAdvanced disease stateProstate cancer developmentNovel therapeutic strategiesCell carcinomaTherapeutic armamentariumTherapeutic strategiesMortality rateCancer developmentMalignancyAndrogensDisease statesCancerCarcinomaProstateArmamentariumMolecular biologyDiseaseProgressionRoleReceptorsDisparities in the Use of Continent Urinary Diversions after Radical Cystectomy for Bladder Cancer
Farber N, Faiena I, Dombrovskiy V, Tabakin A, Shinder B, Patel R, Elsamra S, Jang T, Singer E, Weiss R. Disparities in the Use of Continent Urinary Diversions after Radical Cystectomy for Bladder Cancer. Bladder Cancer 2018, 4: 113-120. PMID: 29430511, PMCID: PMC5798533, DOI: 10.3233/blc-170162.Peer-Reviewed Original ResearchRadical cystectomyIleal conduitIn-hospital complicationsContinent diversionIn-hospital costsLength of stayCD rateBladder cancerMuscle-invasive bladder cancerMalignant bladder neoplasmsMultivariate logistic regression analysisOverall postoperative complicationsAssociated with higher ratesContinent urinary diversionNational Inpatient SampleAssociated with lower ratesLogistic regression analysisUrban teaching centersGeographic disparitiesLarge hospitalsBladder neoplasmsPostoperative complicationsUrinary diversionPatient demographicsStandard treatment