2019
0670 Sleep-Related Event Physiologic Timing for Triggering Nonsustained Ventricular Tachycardia: A Case-crossover Analysis
May A, May R, Bena J, Wang L, Monahan K, Stone K, Barrett-Connor E, Koo B, Winkelman J, Redline S, Mittleman M, Mehra R. 0670 Sleep-Related Event Physiologic Timing for Triggering Nonsustained Ventricular Tachycardia: A Case-crossover Analysis. Sleep 2019, 42: a267-a268. DOI: 10.1093/sleep/zsz067.668.Peer-Reviewed Original ResearchRespiratory eventsSleep-related eventsHazard periodOsteoporotic fracturesOdds ratioBidirectional case-crossover designPeriodic limb movementsRespiratory-related arousalsConditional logistic regressionCase-crossover analysisCase-crossover designPhysiologic timingVentricular tachycardiaNSVTNSVT episodesPhysiologic effectsPLMSOlder menStudy participantsMan studyLogistic regressionLimb movementsSleepControl periodConfidence intervals
2018
Restless legs syndrome and periodic limb movements during sleep in the Multi-Ethnic Study of Atherosclerosis
Doan TT, Koo BB, Ogilvie RP, Redline S, Lutsey PL. Restless legs syndrome and periodic limb movements during sleep in the Multi-Ethnic Study of Atherosclerosis. Sleep 2018, 41: zsy106. PMID: 29860522, PMCID: PMC6093310, DOI: 10.1093/sleep/zsy106.Peer-Reviewed Original ResearchConceptsRestless legs syndromePrevalence of RLSConcurrent restless legs syndromePeriodic limb movementsMulti-Ethnic StudyLegs syndromeObesity statusOdds of RLSLimb movementsPrevalence of PLMSCommunity-based sampleRace/ethnicityRLS symptomsClinical criteriaAdjusted modelPLMSStudy participantsPrevalenceOlder individualsCross-sectional dataAtherosclerosisSexSyndromeWhite participantsSleep1015 Frequent Periodic Limb Movements During Sleep and Risk of Incident Stroke
May A, Koo B, Yaffe K, Leng Y, Cawthon P, Redline S, Stone K, Mehra R. 1015 Frequent Periodic Limb Movements During Sleep and Risk of Incident Stroke. Sleep 2018, 41: a376-a377. DOI: 10.1093/sleep/zsy061.1014.Peer-Reviewed Original ResearchBody mass indexIncident stroke riskPeriodic limb movementsStroke riskIncident strokeMulti-center prospective studyLimb movementsApnea-hypopnea indexAF findingsHypopnea indexMedian ageMedication useTotal cholesterolMass indexSleep apneaArousal indexProspective studyAutonomic dysregulationPhysical activityPLMSSignificant interactionStrokeLogistic regressionAlcohol useAge
2016
Periodic leg movements during sleep: phenotype, neurophysiology, and clinical significance
Ferri R, Koo BB, Picchietti DL, Fulda S. Periodic leg movements during sleep: phenotype, neurophysiology, and clinical significance. Sleep Medicine 2016, 31: 29-38. PMID: 28341521, DOI: 10.1016/j.sleep.2016.05.014.Peer-Reviewed Original ResearchConceptsRestless legs syndromePeriodic leg movementsLeg movementsLeg motor activityLegs syndromePathophysiological correlatesClinical correlatesObjective findingsClinical significanceClinical conditionsNeurophysiologic aspectsCurrent evidencePLMSMotor phenomenaMotor activityAge groupsTypical phenotypeSleepRecent findingsCurrent knowledgeFurther researchCorrelatesFindingsPhenotypeScoring
2015
Restless Legs Syndrome: Would You Like That with Movements or Without?
Koo B. Restless Legs Syndrome: Would You Like That with Movements or Without? Tremor And Other Hyperkinetic Movements 2015, 5: 316. DOI: 10.5334/tohm.280.Peer-Reviewed Original ResearchRestless legs syndromeDiagnosis of RLSRLS diagnosisPeriodic limb movementsSupplementary diagnostic criterionRLS sufferersLegs syndromeSubjective symptomsSleep disturbancesDiagnostic criteriaMotor phenomenaProper diagnosisPatients' descriptionsSensorimotor conditionsPLMSDiagnosisLimb movementsInvestigational levelsPathophysiologySyndromeSymptomsEpidemiologySleepPharmacology