Sex differences in brain gene expression among suicide completers
Cabrera-Mendoza B, Fresno C, Monroy-Jaramillo N, Fries GR, Walss-Bass C, Glahn DC, Ostrosky-Wegman P, Mendoza-Morales RC, García-Dolores F, Díaz-Otañez CE, González-Sáenz EE, Genis-Mendoza AD, Martínez-Magaña JJ, Romero-Pimentel AL, Flores G, Vázquez-Roque RA, Nicolini H. Sex differences in brain gene expression among suicide completers. Journal Of Affective Disorders 2020, 267: 67-77. PMID: 32063575, DOI: 10.1016/j.jad.2020.01.167.Peer-Reviewed Original ResearchMeSH KeywordsBrainFemaleGene Expression ProfilingHumansMalePrefrontal CortexSex CharacteristicsTranscriptomeConceptsBrain gene expressionSex-specific gene expression patternsGene expressionRibonucleic protein complexesGene expression patternsGene expression profilesProtein complexesGene setsDNA bindingExpression patternsExpression profilesGenesSuicide geneBiological levelsVesicular functionCell proliferationValuable foundationDifferentiallyMicroarrayExpressionSex-specific factorsSuicide completersSuicidal brainImmune responseSex differencesBrain Gene Expression Profiling of Individuals With Dual Diagnosis Who Died by Suicide
Cabrera-Mendoza B, Fresno C, Monroy-Jaramillo N, Fries GR, Walss-Bass C, Glahn DC, Ostrosky-Wegman P, Genis-Mendoza AD, Martínez-Magaña JJ, Romero-Pimentel AL, Díaz-Otañez CE, García-Dolores F, González-Sáenz EE, Mendoza-Morales RC, Flores G, Vázquez-Roque R, Nicolini H. Brain Gene Expression Profiling of Individuals With Dual Diagnosis Who Died by Suicide. Journal Of Dual Diagnosis 2019, 16: 177-190. PMID: 31774731, DOI: 10.1080/15504263.2019.1692160.Peer-Reviewed Original ResearchConceptsSubstance use disordersMood disordersDual diagnosisUse disordersMental comorbiditiesGene expression profilesMental disordersSingle disorderCell type enrichmentAdverse clinical outcomesGlial-specific markersMore mental disordersExpression profilesDorsolateral prefrontal cortexClinical outcomesGABAergic neurotransmissionGlial markersHigh riskDisorder patientsComorbiditiesSuicidal behaviorPrefrontal cortexGene expression profilingSynaptic genesDisorders