2022
Some Like It Hot—A Commentary to Ex Vivo Normothermic Perfusion of Human Upper Limbs
Haug V, Diehm Y, Kneser U, Pomahac B. Some Like It Hot—A Commentary to Ex Vivo Normothermic Perfusion of Human Upper Limbs. Transplantation 2022, 106: 1522-1523. PMID: 35152258, DOI: 10.1097/tp.0000000000004046.Peer-Reviewed Original Research
2018
Reduced Hypoxia-Related Genes in Porcine Limbs in Ex Vivo Hypothermic Perfusion Versus Cold Storage
Krezdorn N, Sakthivel D, Turk M, Aycart M, Tasigiorgos S, Bueno E, Sinha I, Pomahac B. Reduced Hypoxia-Related Genes in Porcine Limbs in Ex Vivo Hypothermic Perfusion Versus Cold Storage. Journal Of Surgical Research 2018, 232: 137-145. PMID: 30463709, DOI: 10.1016/j.jss.2018.05.067.Peer-Reviewed Original ResearchConceptsStatic cold storagePerfusion groupIschemia-reperfusion injuryPCR gene arrayPorcine limbsMuscle fiber disruptionIschemic injuryPerfadex solutionPerfused limbMachine perfusionHypothermic perfusionHistological changesPreservation modalityMuscle biopsyLimb replantationPerfusionICE groupLess activationPorcine forelimbDownregulation of genesMolecular changesLimbFiber disruptionExpression levelsReplantation
2017
The promise of organ and tissue preservation to transform medicine
Giwa S, Lewis J, Alvarez L, Langer R, Roth A, Church G, Markmann J, Sachs D, Chandraker A, Wertheim J, Rothblatt M, Boyden E, Eidbo E, Lee W, Pomahac B, Brandacher G, Weinstock D, Elliott G, Nelson D, Acker J, Uygun K, Schmalz B, Weegman B, Tocchio A, Fahy G, Storey K, Rubinsky B, Bischof J, Elliott J, Woodruff T, Morris G, Demirci U, Brockbank K, Woods E, Ben R, Baust J, Gao D, Fuller B, Rabin Y, Kravitz D, Taylor M, Toner M. The promise of organ and tissue preservation to transform medicine. Nature Biotechnology 2017, 35: 530-542. PMID: 28591112, PMCID: PMC5724041, DOI: 10.1038/nbt.3889.Peer-Reviewed Original Research
2014
Fortschritte in der Gesichtstransplantation
Kueckelhaus M, Lehnhardt M, Fischer S, Eriksson E, Pomahac B, Hirsch T. Fortschritte in der Gesichtstransplantation. Handchirurgie · Mikrochirurgie · Plastische Chirurgie 2014, 46: 206-213. PMID: 25162238, DOI: 10.1055/s-0034-1385850.Peer-Reviewed Original ResearchConceptsVascularised composite allotransplantationFace transplantationLife-threatening side effectsSolid organ transplantationDifferent transplant centersImmunosuppressive regimensMaintenance immunosuppressionVCA proceduresImmunosuppressive strategiesTransplant centersPatients' qualityLifelong immunosuppressionOrgan preservationSurgical techniqueOrgan transplantationComposite allograftsComposite allotransplantationSide effectsTransplantationFunctional reintegrationImmunosuppressionAnatomic structuresImmunogenic partFirst caseDifferent protocols