2015
Initial Experience of Dual Maintenance Immunosuppression With Steroid Withdrawal in Vascular Composite Tissue Allotransplantation
Diaz-Siso J, Fischer S, Sisk G, Bueno E, Kueckelhaus M, Talbot S, Carty M, Treister N, Marty F, Milford E, Pomahac B, Tullius S. Initial Experience of Dual Maintenance Immunosuppression With Steroid Withdrawal in Vascular Composite Tissue Allotransplantation. American Journal Of Transplantation 2015, 15: 1421-1431. PMID: 25777324, DOI: 10.1111/ajt.13103.Peer-Reviewed Original ResearchConceptsAcute rejectionVCA recipientsMaintenance immunosuppressionSteroid-resistant acute rejectionLate acute rejectionSolid organ transplantationComposite tissue allotransplantationMaintenance steroidsTopical immunosuppressionCurrent immunosuppressionSteroid withdrawalBolus treatmentOrgan transplantationLow doseImmunosuppressionTissue allotransplantationInitial experienceFurther experienceSteroidsRecipientsTacrolimusPatientsTreatmentMonthsLow levels
2014
Acute rejection in vascularized composite allotransplantation
Fischer S, Lian C, Kueckelhaus M, Strom T, Edelman E, Clark R, Murphy G, Chandraker A, Riella L, Tullius S, Pomahac B. Acute rejection in vascularized composite allotransplantation. Current Opinion In Organ Transplantation 2014, 19: 531-544. PMID: 25333831, DOI: 10.1097/mot.0000000000000140.Peer-Reviewed Original ResearchConceptsAcute rejection episodesAcute rejectionRejection episodesComposite allotransplantationDepth histological analysisHigh-dose steroidsLong-term safetyField of transplantationBetter diagnostic toolsFace transplant recipientsMaintenance immunosuppressionSteroid withdrawalTransplant recipientsCommon complicationImmunologic eventsAppropriate therapyPatient numbersTimely institutionRestorative surgeryDose reductionEarly diagnosisMost episodesNovel biomarkersHigh immunogenicityPatient care