2023
Work difficulties, work restrictions, and disability benefits in people with functional seizures: A survey study
Woodward J, Asadi-Pooya A, Mildon B, Tolchin B. Work difficulties, work restrictions, and disability benefits in people with functional seizures: A survey study. Epilepsy & Behavior Reports 2023, 23: 100610. PMID: 37645697, PMCID: PMC10460675, DOI: 10.1016/j.ebr.2023.100610.Peer-Reviewed Original ResearchFunctional seizuresWork restrictionsSignificant long-term disabilityOlder ageDisability benefitsLogistic regressionLong-term disabilityWork difficultiesPredictors of unemploymentExperienced disabilityDisability limitationsSeizuresPotential predictorsWork limitationsDemographic informationCurrent employment statusWork accommodationsDisabilityMajority of peopleCliniciansMost respondentsEmployment statusHigh percentageAgePredictors
2022
Visually sensitive seizures: An updated review by the Epilepsy Foundation
Fisher RS, Acharya JN, Baumer FM, French JA, Parisi P, Solodar JH, Szaflarski JP, Thio LL, Tolchin B, Wilkins AJ, Trenité D. Visually sensitive seizures: An updated review by the Epilepsy Foundation. Epilepsia 2022, 63: 739-768. PMID: 35132632, DOI: 10.1111/epi.17175.Peer-Reviewed Original ResearchConceptsPhotosensitive seizuresAntiseizure drugsPhotoparoxysmal responseEpilepsy FoundationPrevention of seizuresLight-induced seizuresWhite matter tractsSignificant public health hazardSpontaneous seizuresNonsystematic literature reviewGeneralized epilepsyPublic health hazardPhotosensitivity modelAbnormal connectivityOccipital cortexProvocative stimuliSeizuresVisual fieldVisual stimulationBrain imagingColor flashesUpdated reviewEpilepsySelection biasDrugs
2021
Neurology residents’ education in functional seizures
Milligan T, Yun A, LaFrance W, Baslet G, Tolchin B, Szaflarski J, Wong V, Plioplys S, Dworetzky B. Neurology residents’ education in functional seizures. Epilepsy & Behavior Reports 2021, 18: 100517. PMID: 35243288, PMCID: PMC8857462, DOI: 10.1016/j.ebr.2021.100517.Peer-Reviewed Original ResearchFunctional neurological disorderFunctional seizuresNeurology residentsNeurology residency program directorsResidency program directorsEpilepsy monitoring unitEvidence-based treatmentsNeurology resident educationProgram directorsLow response rateResponse rateNeurological disordersFrequent settingPatientsMajority of programsDiagnosisNeurology residencySeizuresClinical rotationsResident educationTreatmentResidencyCurriculum gapsStandardized modelDidactic lecturesHow to do things with words Two seminars on the naming of functional (psychogenic, non-epileptic, dissociative, conversion, …) seizures
Wardrope A, Dworetzky BA, Barkley GL, Baslet G, Buchhalter J, Doss J, Goldstein LH, Hallett M, Kozlowska K, LaFrance WC, McGonigal A, Mildon B, Oto M, Perez DL, Riker E, Roberts NA, Stone J, Tolchin B, Reuber M. How to do things with words Two seminars on the naming of functional (psychogenic, non-epileptic, dissociative, conversion, …) seizures. Seizure 2021, 93: 102-110. PMID: 34740139, PMCID: PMC9308960, DOI: 10.1016/j.seizure.2021.10.016.Peer-Reviewed Original ResearchConceptsPsychogenic non-epileptic seizuresNon-epileptic attack disorderFunctional seizuresDissociative seizuresNon-epileptic seizuresAmerican Epilepsy SocietyHealth care systemNew diagnostic labelSynchronous electrical activityPatient responseDifferential diagnosisEpilepsy SocietyAttack disorderConversion disorderEpileptic seizuresSeizuresCare systemElectrical activityDiagnostic labelsDiagnosisDisordersEpilepsyPseudoseizuresBrainParoxysmsFunctional seizures are not less important than epilepsy
Asadi-Pooya AA, Brigo F, Tolchin B, Valente KD. Functional seizures are not less important than epilepsy. Epilepsy & Behavior Reports 2021, 16: 100495. PMID: 34805820, PMCID: PMC8585631, DOI: 10.1016/j.ebr.2021.100495.Peer-Reviewed Original ResearchFunctional Seizures
Marcolini E, Tolchin B. Functional Seizures. Emergency Medicine Clinics Of North America 2021, 39: 123-132. PMID: 33218653, DOI: 10.1016/j.emc.2020.09.007.Peer-Reviewed Original ResearchConceptsFunctional seizuresEpileptic seizuresFunctional neurologic disordersElectroencephalography findingsPsychogenic seizuresTherapeutic challengeClinical historyEpileptic dischargesNeurologic disordersConversion disorderSeizuresMental illnessBiopsychosocial modelDisordersSocial factorsSymptomsIllness
2019
Randomized controlled trial of motivational interviewing for psychogenic nonepileptic seizures
Tolchin B, Baslet G, Suzuki J, Martino S, Blumenfeld H, Hirsch LJ, Altalib H, Dworetzky BA. Randomized controlled trial of motivational interviewing for psychogenic nonepileptic seizures. Epilepsia 2019, 60: 986-995. PMID: 30980679, DOI: 10.1111/epi.14728.Peer-Reviewed Original ResearchConceptsPsychogenic nonepileptic seizuresQuality of lifeMI participantsPNES frequencyMotivational interviewingControl participantsNonepileptic seizuresQuaternary care medical centerEmergency department visitsEmergency department utilizationSingle neurologistDepartment visitsTreatment adherenceControl armMedical CenterMI armsSeizuresVisitsTrialsAdherenceParticipantsPsychotherapyAdherentArmReferralAdherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures.
Tolchin B, Dworetzky BA, Martino S, Blumenfeld H, Hirsch LJ, Baslet G. Adherence with psychotherapy and treatment outcomes for psychogenic nonepileptic seizures. Neurology 2019, 92: e675-e679. PMID: 30610097, PMCID: PMC6382361, DOI: 10.1212/wnl.0000000000006848.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAdult Survivors of Child AbuseAgedAged, 80 and overCohort StudiesConversion DisorderEmergency Service, HospitalEthnicityFemaleFollow-Up StudiesHumansMaleMiddle AgedMinority GroupsOdds RatioProspective StudiesPsychotherapyQuality of LifeSeizuresTreatment Adherence and ComplianceTreatment OutcomeYoung AdultConceptsPsychogenic nonepileptic seizuresQuality of lifePNES frequencyNonepileptic seizuresProspective cohort studyEmergency department utilizationTime of referralBaseline characteristicsCohort studyED visitsSeizure frequencyED utilizationPotential confoundersWomen's HospitalTreatment outcomesMedium effect sizeLocal therapistsMultivariate modelAdherenceChildhood abuseSeizuresHospitalSignificant reductionOutcomesEffect size
2017
Nonepileptic Psychogenic Status Epilepticus
Tolchin B, Dworetzky B. Nonepileptic Psychogenic Status Epilepticus. Current Clinical Neurology 2017, 31-42. DOI: 10.1007/978-3-319-58200-9_4.Peer-Reviewed Original ResearchPsychogenic nonepileptic seizuresPsychogenic status epilepticusStatus epilepticusDifferential diagnosisNonconvulsive status epilepticusImportant differential diagnosisSeizure semiologyClinical historyIatrogenic harmNonepileptic seizuresEpilepticusEpileptic seizuresDiagnosisGold standardSupportive testsSeizuresPatientsPrognosisEtiologyEpidemiologyMortalityAssociation of Periodic and Rhythmic Electroencephalographic Patterns With Seizures in Critically Ill Patients
Ruiz A, Vlachy J, Lee JW, Gilmore EJ, Ayer T, Haider HA, Gaspard N, Ehrenberg JA, Tolchin B, Fantaneanu TA, Fernandez A, Hirsch LJ, LaRoche S. Association of Periodic and Rhythmic Electroencephalographic Patterns With Seizures in Critically Ill Patients. JAMA Neurology 2017, 74: 181-188. PMID: 27992625, DOI: 10.1001/jamaneurol.2016.4990.Peer-Reviewed Original ResearchConceptsRhythmic delta activityDelta activityPeriodic dischargesIll patientsSeizure riskElectroencephalographic patternsStimulation-induced patternsCritically Ill PatientsRisk of seizuresHigher seizure riskAcademic medical centerFrequency-dependent mannerSeizure incidenceIll adultsRisk stratificationHigh prevalenceMedical CenterMAIN OUTCOMEContinuous electroencephalographySeizuresPattern prevalenceMultivariate analysisPatientsClinical decisionRhythmic patterns