Oncologic outcomes of neoadjuvant chemotherapy in patients with micropapillary variant urothelial carcinoma of the bladder
Rahman S, Lokeshwar S, Syed J, Javier-Desloges J, Press B, Choksi A, Rajwa P, Pradere B, Ploussard G, Kim J, Monaghan T, Renzulli J, Shariat S, Leapman M. Oncologic outcomes of neoadjuvant chemotherapy in patients with micropapillary variant urothelial carcinoma of the bladder. Urologic Oncology Seminars And Original Investigations 2022, 41: 107.e1-107.e8. PMID: 36481253, DOI: 10.1016/j.urolonc.2022.09.008.Peer-Reviewed Original ResearchConceptsVariant urothelial carcinomaNeoadjuvant chemotherapySubset of patientsUrothelial carcinomaOverall survivalPathologic responseRadical cystectomyNAC useClinical stage II diseaseHospital-based registry studyNeoadjuvant platinum-based chemotherapyPathologic lymph node positivityCox proportional hazards modelNational Cancer DatabaseStage II diseaseLymph node positivityPathologic complete responsePlatinum-based chemotherapyKaplan-Meier analysisMultivariable logistic regressionAnalysis of patientsBladder urothelial carcinomaProportional hazards modelCT2 diseasePathologic upstagingSurveillance and office management of low-grade Ta bladder tumors
Lokeshwar SD, Rahman SN, Press BH, Khan AI, Soloway MS. Surveillance and office management of low-grade Ta bladder tumors. Actas Urológicas Españolas (English Edition) 2022, 46: 613-618. PMID: 35780050, DOI: 10.1016/j.acuroe.2022.01.004.Peer-Reviewed Original ResearchMeSH KeywordsHumansOffice ManagementQuality of LifeRetrospective StudiesUrinary BladderUrinary Bladder NeoplasmsConceptsBladder cancerBladder tumorsRetrospective case series analysisBladder preservation protocolT2 bladder cancerT1 bladder cancerTa bladder cancerCase series analysisQuality of lifeLG TaSystemic immunotherapyIntravesical chemotherapyPrimary outcomeTransurethral resectionHispanic patientsRecurrent tumorsOffice managementActive surveillanceCurrent guidelinesCommon treatmentPatientsStage progressionGrade 1TumorsCautery