Utility of PSA Density in Predicting Upgraded Gleason Score in Men on Active Surveillance With Negative MRI
Press BH, Khajir G, Ghabili K, Leung C, Fan RE, Wang NN, Leapman MS, Sonn GA, Sprenkle PC. Utility of PSA Density in Predicting Upgraded Gleason Score in Men on Active Surveillance With Negative MRI. Urology 2021, 155: 96-100. PMID: 34087311, DOI: 10.1016/j.urology.2021.05.035.Peer-Reviewed Original ResearchConceptsPSA densityActive surveillanceConfirmatory biopsyPathologic upgradeNegative MRIProstate volumeProstate cancerFavorable intermediate-risk prostate cancerNegative baselineIntermediate-risk prostate cancerLow-grade prostate cancerLower prostate volumeMedian PSA densityNormal baseline MRIUpgraded Gleason scoreCohort of patientsSubset of patientsLarge academic centerPI-RADS 2Intensity of surveillanceAbility of PSABiopsy upgradeGG1 cancerGleason upgradeMedian PSA