Dopamine and norepinephrine innervated cells in the rat prefrontal cortex: Pharmacological differentiation using microiontophoretic techniques
Bunney B, Aghajanian G. Dopamine and norepinephrine innervated cells in the rat prefrontal cortex: Pharmacological differentiation using microiontophoretic techniques. Life Sciences 1976, 19: 1783-1792. PMID: 1004134, DOI: 10.1016/0024-3205(76)90087-4.Peer-Reviewed Original ResearchConceptsRat prefrontal cortexMicroiontophoretic techniquesLayer VLayers IIPrefrontal cortexUptake blockersInhibitory effectNE uptake blockerDA receptor blockerCortical layers IIDA uptake blockersReceptor blockersDA inhibitionNoradrenergic projectionsAccumbens nucleusPharmacological differentiationNorepinephrineCell activitySensitivity of cellsHistochemical evidenceBlockersCortexDopamineSensitive cellsSuperficial layers