Effects of molindone on central dopaminergic neuronal activity and metabolism: similarity to other neuroleptics.
Bunney B, Roth R, Aghajanian G. Effects of molindone on central dopaminergic neuronal activity and metabolism: similarity to other neuroleptics. Psychopharmacology Communications 1975, 1: 349-58. PMID: 1224004.Peer-Reviewed Original ResearchConceptsEffects of molindoneCentral dopaminergic neuronal activityExtracellular single-unit recordingsLow intravenous dosesDopaminergic neuronal activityDA neuron activityMost antipsychotic drugsBaseline firing rateSingle-unit recordingsDA metabolismDA neuronsIntravenous dosesClassical neurolepticsDopaminergic neuronsOlfactory tubercleDA cellsAntipsychotic drugsD-amphetamineInduced depressionRat midbrainDopamine synthesisNeuronal activityUnit recordingsNeuron activityMolindone