1992
Roles of intracellular cAMP and protein kinase A in the actions of dopamine and neurotensin on midbrain dopamine neurons
Shi W, Bunney B. Roles of intracellular cAMP and protein kinase A in the actions of dopamine and neurotensin on midbrain dopamine neurons. Journal Of Neuroscience 1992, 12: 2433-2438. PMID: 1318960, PMCID: PMC6575923, DOI: 10.1523/jneurosci.12-06-02433.1992.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCyclic AMPDopamineIntracellular MembranesMaleMesencephalonNeural InhibitionNeuronsNeurotensinProtein KinasesRatsRats, Inbred StrainsConceptsDopamine-induced inhibitionEffects of neurotensinDopamine neuronsIntracellular cAMPAdenylate cyclaseAction of neurotensinRat midbrain slicesAction of dopamineVentral tegmental areaMidbrain dopamine neuronsIntracellular cAMP levelsMidbrain slicesSubstantia nigraTegmental areaDopamine cellsDopamine effectsSpontaneous activityModulatory effectsNeurotensinIsobutyl methylxanthineInhibitory effectNeuronsCAMP levelsProtein kinase CInhibition
1983
Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—1. Identification and characterization
Grace A, Bunney B. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—1. Identification and characterization. Neuroscience 1983, 10: 301-315. PMID: 6633863, DOI: 10.1016/0306-4522(83)90135-5.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsApomorphineDopamineElectrophysiologyExtracellular SpaceIntracellular MembranesMaleNeuronsRatsRats, Inbred StrainsSubstantia NigraConceptsAction potentialsDopamine neuronsDopamine cellsGlyoxylic acid-induced catecholamine fluorescenceInput resistanceDopamine synthesizing enzymePostsynaptic target areasIntracellular dopamine contentNigral dopamine cellsPossible modulatory effectDopamine-containing cellsIntracellular dopamine concentrationSame inhibitory effectHigh input resistanceInitial segmentAntidromic activationDopaminergic neuronsDopamine contentIntracellular recordingsDopamine synthesisCaudate nucleusElectrophysiological characteristicsTyrosine hydroxylaseCatecholamine fluorescenceModulatory effectsIntracellular and extracellular electrophysiology of nigral dopaminergic neurons—2. Action potential generating mechanisms and morphological correlates
Grace A, Bunney B. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—2. Action potential generating mechanisms and morphological correlates. Neuroscience 1983, 10: 317-331. PMID: 6633864, DOI: 10.1016/0306-4522(83)90136-7.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsDendritesElectrophysiologyEvoked PotentialsExtracellular SpaceIntracellular MembranesMaleNeuronsRatsRats, Inbred StrainsSubstantia NigraConceptsInitial segment spikesDopamine neuronsSlow depolarizationAction potentialsAxon hillockDendritic dopamine releaseLong-duration afterhyperpolarizationNigral dopamine neuronsLow-threshold spikesLucifer yellow injectionExtracellular recording techniquesLong-duration spikesAction potential generationDopaminergic neuronsSpecific ionic currentsIntracellular recordingsDopamine releaseIntracellular injectionElectrophysiological studiesDendritic spikesMajor dendritesNeuron 2Action potential generating mechanismSomatic regionNeuronal compartments