1996
Effects of Lesions in the Medial Prefrontal Cortex on the Activity of Midbrain Dopamine Neurons
Shim S, Bunney B, Shi W. Effects of Lesions in the Medial Prefrontal Cortex on the Activity of Midbrain Dopamine Neurons. Neuropsychopharmacology 1996, 15: 437-441. PMID: 8914116, DOI: 10.1016/s0893-133x(96)00052-8.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsExcitatory Amino Acid AgonistsIbotenic AcidInjections, IntraventricularMaleMesencephalonNeuronsPatch-Clamp TechniquesPrefrontal CortexRatsRats, Sprague-DawleyReceptors, DopamineConceptsVentral tegmental areaDA neuronsPrefrontal cortexSubstantia nigraPFC lesionsBursting activityFiring rateActive DA cellsSN DA neuronsActive DA neuronsMidbrain dopamine neuronsSingle-unit recordingsMedial prefrontal cortexDA cellsDopamine neuronsTegmental areaLocal injectionIbotenic acidUnit recordingsLesionsSame lesionNeuronsRatsActivityCortex
1990
Neurotensin attenuates dopamine D2 agonist quinpirole-induced inhibition of midbrain dopamine neurons
Shi W, Bunney B. Neurotensin attenuates dopamine D2 agonist quinpirole-induced inhibition of midbrain dopamine neurons. Neuropharmacology 1990, 29: 1095-1097. PMID: 1982340, DOI: 10.1016/0028-3908(90)90119-c.Peer-Reviewed Original ResearchConceptsD2 agonistDA cellsSingle-unit recording techniquesMidbrain DA neuronsCentral DA systemsDopamine D2 agonistMidbrain dopamine neuronsSpecific D2 agonistDA neuronsIntracerebroventricular administrationDopamine neuronsSpontaneous activityDA systemInhibitory effectRecording techniquesAgonistsNeuronsBiochemical studiesCellsQuinpiroleNeurotensinRatsAdministration